Fibrous palygorskite clays as versatile nanocarriers for skin delivery of tea tree oils in efficient acne therapy

Construction of tea tree oil/salicylic acid/palygorskite hybrids for advanced antibacterial and anti-inflammatory performance

“…Similar results have also been found for TTO-Pal and free TTO, which exhibited a preferential inhibition of pathogenic bacteria (E. coli and S. aureus) over S. epidermidis. 16,49 Taken together, TSP-1 exhibited both time-dependent and dose-dependent inhibition of skin commensal bacteria with more pronounced bactericidal effects against E. coli, followed by S. aureus and P. acnes and then S. epidermidis, which is consistent with the MIC and MBC results.…”

“…Similar XRD and TEM results were also reported in our previous study on TTO-Pal hybrids, which suggests that the simple solvent evaporation method adopted in both studies is advantageous. 16 The surface areas of samples, measured by the classical N 2 chemisorption method, showed a decreasing trend from pristine Pal to double-component systems and then the more complex triple-component systems (Table 1). The results illustrate that the coverage of biomolecules on the Pal surface may result in blocking the access of N 2 into the Pal channels during BET measurement.…”

“…The irritancy was quantified using S-scores calculated from the three endpoints as previously described. 34 2.5 In vitro antibacterial activity 2.5.1 MIC and MBC determination. Microbiological analyses were performed using bacterial strains of E. coli (ATCC 25922), S. epidermis (isolated from the microbiota of a healthy Chinese male donor), S. aureus (ATCC 25923), and P. acnes (ATCC 6919), according to the M07-A9 method described by the Clinical and Laboratory Standards Institute 35 and the M11-A6 method described by the National Committee for Clinical Laboratory Standards.…”

Effects of dietary supplementation with different levels of palygorskite-based composite on growth performance, antioxidant capacity, and meat quality of broiler chickens

“…However, clay minerals usually cannot be adsorbed in gastrointestinal tract and enter into blood circulation, and therefore their beneficial effects on redox status in blood and internal organs may be limited to extra corporeal circuits. The loaded active substances with favorable antioxidant activity on Pal such as zinc and essential oil usually can be digested and absorbed by animals ( Li et al, 2015 ; Tang et al, 2015 ; Yang et al, 2016 ; Oceľová et al, 2019 ; Zhang et al, 2022 ), which may provide another possible explanation for the improved redox status of broilers observed in this study. The synergistic effect between Pal and the loaded active substances has been proven both in vitro ( Lei et al, 2017 ; Zhong et al, 2021 ) and in vivo ( Hu et al, 2012 ; Yan et al, 2016 ).…”

“…Likewise, an incorporation of Pal-adsorbed nano ZnO was reported to be beneficial for maintenance of intestinal barrier function in weanling piglets ( Yu et al, 2022 ). In addition to this, the loaded bioactive substances in PBC are actually available and therefore can be absorbed by the gastrointestinal tract ( Yan et al, 2016 ; Yang et al, 2016 , 2017a , b ; Oceľová et al, 2019 ; Zhang et al, 2022 ), which would also contribute to the improved feed conversion efficiency, mainly due to their multiple biological functions as summarized previously ( Abd El-Hack et al, 2017 , 2022 ).…”