The advent of compact, high-performance optical sensors of strain and temperature based on frequencydomain interrogation of special optical fibers yields many unique opportunities for sensing in environments that are challenging for traditional sensor technologies. An intriguing application is the use of fiber Bragg grating (FBG) sensors to collect critical structural, thermal, and even acoustic data throughout the launch vehicle and spacecraft engineering lifecycle, including during flight.Fiber Bragg Grating sensors are formed from special optical perturbations of a communications-grade optical fiber, and act as high sensitivity, low mass, electrically passive, and electrically immune detectors of structural strain, temperature, and other quantities; the serial architecture and embeddable sensor element with very small cross section make FBGs an attractive solution for minimally invasive instrumentation of both ground test and flight test experiments, especially where traditional (piezoelectric, foil-resistive) sensors are impractical due to harsh environmental conditions.In this paper, several elements of the state of the art of FBG sensors are detailed with a focus on the necessary technology development steps required to employ FBGs as a critical, enabling technology for collection of mission-critical structural dynamics, thermal, and subsystem health data in harsh flight environments. Current capabilities and limitations are detailed in the context of this unique application where existing commercial and research-grade sensor systems have not yet been extensively deployed.