Field trials of a food-based vaccine to protect village chickens against Newcastle disease

Aini, I.; Ibrahim, Ab Latif; Spradbrow, P. B.

doi:10.1016/s0034-5288(18)31080-4

Cited by 34 publications

(23 citation statements)

References 2 publications

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“…Earlier reports on similar investigations showed varying outcomes (Ideris et al, 1978a, Aini et al, 1990b. Failure of some of these trials was blamed on antiviral factors constituent in the seeds or introduced as preservatives.…”

Section: Discussionmentioning

confidence: 99%

Delivery of thermostable Newcastle disease (ND) vaccine to chickens with broken millet grains as the vehicle

G¹,

Iroegbu²,

C³

et al. 2007

Afr. J. Biotechnol.

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Section: Discussionmentioning

confidence: 99%

Delivery of thermostable Newcastle disease (ND) vaccine to chickens with broken millet grains as the vehicle

G¹,

Iroegbu²,

C³

et al. 2007

Afr. J. Biotechnol.

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“…While there are no published data for the prevalence of NDV antibodies in rural chickens in Viet Nam, it is estimated (Pham Hong Son, personal communication) to range between 40-60%. This is higher than the 10% reported from Malaysia (Aini and Ibrahim, 1990) but lower than the sero-prevalence of 62.9-72% reported from Nigeria (Ezeokoli et al, 1984). There are several possible reasons for this low level of protection in vaccinated birds, such as poor vaccine quality, unsuitable vaccination schedule or vaccination technique, impaired immune-competence due to immune-suppressive substances in the feed or to immune-suppressive Our results also show considerable differences diseases.…”

Section: Discussionmentioning

confidence: 52%

Antibody Levels against Newcastle Disease Virus, Infectious Bursal Disease Virus and Avian Influenza Virus in Rural Chickens in Viet Nam

Vui¹,

Lohr²,

Kyule

et al. 2002

International J. of Poultry Science

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A serological survey on the prevalence of antibodies to Newcastle Disease (ND) virus, Infectious Bursal disease (IBD) virus and Avian Influenza (AI) virus was carried out in two communes of the Hue District, Middle Viet Nam. The villages in each commune and the households in each village included approximately 10% scavenging and 20% backyard chickens. The main objectives were to determine the prevalence of antibodies against ND virus at different seasons of the year, the prevalence of antibodies against IBD and AI virus, and a comparison of the situation of ND, IBD and AI in scavenging and backyard chickens. The results showed that there was no statistically significant difference in NDV titres between the seasons and between ND vaccinated and unvaccinated birds but there was a significant difference between the unvaccinated scavenging (33.9%) and the unvaccinated backyard birds (21.6%). Both ND vaccinated and unvaccinated birds in the 2-<6 months-old groups had a significantly lower NDV antibody titre than the > 6 month-old age group. There was no overt correlation between NDV-HI-and IBDV-ELISA titres. A statistical analysis was precluded due to inadequate data sets. There were 5 reactors in the AI-ELISA but they were negative in the HI test with H and H HA antigens. This study showed that in the selected chicken population 5 7 the level of protection of vaccinated birds was unsatisfactory. It further showed that there was no seasonal difference between rainy and dry season, that IBDV existed but did not appear to be associated with NDV. There were no specific antibodies against the H /H subtypes of AIV.

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“…These NDV isolates have several advantages in that they are thermostable, avirulent, spread between chickens, and easily administered through drinking water, sprays and food. Thus, they have been widely used as vaccines to control Newcastle disease for village flocks (Aini et al, 1990). Following the establishment of reverse genetics systems for NDV, many thermolabile NDV strains have been developed as vaccine vectors for the generation of bivalent vaccines against avian diseases.…”

Section: Discussionmentioning

confidence: 99%

“…Newcastle disease vaccine strains, such as LaSota and Hitchner B1, have been used widely in commercial flocks. However, these vaccines are not generally suitable for village flocks (Aini et al, 1990). The main problem associated with these vaccines is their thermoinstability and subsequent requirement of a cold chain for the delivery of viable vaccines to villages.…”

Section: Introductionmentioning

confidence: 99%

Development of a novel thermostable Newcastle disease virus vaccine vector for expression of a heterologous gene

Wen

Chen

Guo

et al. 2015

Journal of General Virology

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Field trials of a food-based vaccine to protect village chickens against Newcastle disease

Cited by 34 publications

References 2 publications

Delivery of thermostable Newcastle disease (ND) vaccine to chickens with broken millet grains as the vehicle

Delivery of thermostable Newcastle disease (ND) vaccine to chickens with broken millet grains as the vehicle

Antibody Levels against Newcastle Disease Virus, Infectious Bursal Disease Virus and Avian Influenza Virus in Rural Chickens in Viet Nam

Development of a novel thermostable Newcastle disease virus vaccine vector for expression of a heterologous gene

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