Field Trials of a Vaccine with Water-soluble Adjuvant for Bacterial Coldwater Disease in Ayu Plecoglossus altivelis

Nagai, Tatsuo; Iida, Yasuo; Yoneji, Takashi

doi:10.3147/jsfp.38.63

Cited by 12 publications

(2 citation statements)

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“…Treatment with antimicrobial drugs was often ineffective to control the disease even in farmed ayu, and thus considerable efforts have been paid for vaccine development against BCWD in ayu. It has been reported that intraperitoneal injections of formalin killed bacterin combined with oil or water-soluble adju vants were effective in ayu under laboratory conditions (Rahman et al, 2000(Rahman et al, , 2003, and a vaccine with water soluble adjuvant was effective against spontaneously occurring BCWD in field trials (Nagai et al, 2003). The efficacy of oral vaccination with formalin-killed bacterin has been also reported (Kondo et al, 2003).…”

mentioning

confidence: 97%

Differences in Susceptibility to Flavobacterium psychrophilum among Three Stocks of Ayu Plecoglossus altivelis

Nagai¹,

Tamura

Iida³

et al. 2004

Fish Pathol.

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mentioning

confidence: 97%

Differences in Susceptibility to Flavobacterium psychrophilum among Three Stocks of Ayu Plecoglossus altivelis

Nagai¹,

Tamura

Iida³

et al. 2004

Fish Pathol.

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“…Since sweet fish is annual and all of its organs are edible, this longterm residual adjuvant vaccine is not a suitable choice of vaccine [85]. Further developments of a water-soluble adjuvant and its effectiveness with a short residence period have also been demonstrated [86][87][88].…”

Section: Bacterial Cold-water Diseasementioning

confidence: 99%

Zoonosis and Vaccination for Fish Health Managment

Kumar,

Middha,

Menon

et al. 2024

Preprint

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Vaccination is an important method of immunological preventive care required for health management of all animal including fish. More particularly, immunization is important in in-land fisheries for the management of diseases in fish brood stocks and healthy seed production. According to the latest statistics in 2020, 90.3 million tonnes of captured fish production was achieved from the aquaculture sector. Out of the above, 78.8 million tonnes from marine and 11.5 million tonnes from inland waters aquaculture sectors. About 4% decline in fish production was achieved in 2020 than 2018 from inland fisheries sectors. On the other hand, the digestive protein content, healthy fats and nutritional values of fish products are comparitively more affordable as compared to other meat sources. In 2014, about 10% aquatic cultured animals were lost (costing &gt; 10 billion $ global annual loss) due to infectious diseases. Therefore, vaccination in fish especially in brood stocks is one of the most important approaches to stop such losses in the fisheries sector. Fish vaccines consist of either whole killed pathogens, subunit of a protein, a recombinant protein, DNA vaccines or live attenuated vaccines. Challenges existing are adaption of vaccination in fisheries sector, route of administration, use of effective adjuvants and most importantly lack of effective results. Use of autogenous vaccines, vaccination via intramuscular, intraperitoneal or oral routes, and most importantly adding vaccines in feed using top dressing methods or as a constituent in fish feed are now in emerging. These method shall lower the risk of using antibiotics in cultured water which in turn will reduce the environmental contamination.

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