Field trials of double translocation heterozygote males for genetic control ofAedes aegypti(L.) (Diptera: Culicidae)

Abstract

For nine weeks from 14 April to 13 June 1975 an average of over 500 double translocation heterozygote male Aedes aegypti (L.) were released daily into a village where the estimated adult mosquito population was 1200. The two purposes of this release were to suppress the A. aegypti population by sterility induced by chromosomal translocations and to assess the effect of rainy season conditions on the population dynamics of the indigenous and released mosquitoes. As a result of the releases, hatcha'bility of eggs from females collected during landing-biting catches dropped from over 93% to 30-40%. For eight weeks following the termination of the releases, hatchability remained below 70 % while that of the reference village averaged between 80 and 99 % hatch. A relative population decline observed in the release village is not attributed solely to the effect of the releases, partly because it occurred before sufficient time had elapsed to allow induced sterility to build up in the field population.

The need for new vector control approaches targeting outdoor biting anopheline malaria vector communities

“…Wild females that mate with sterile males do not produce viable offspring. SITs have been successfully deployed against a variety of insect pests but have so far had limited success against mosquito vector control [98][99][100][101][102][103][104][105][106][107][108]. For the control of large and complex African malaria vector populations, SIT is usually not considered a realistic strategy due to the large scale of releases required [109].…”

Long-term survival of introduced genes in a natural population of Aedes Aegypti (L.) (Diptera: Culicidae)

“…Schemes for genetic control (other than releases of completely sterile insects) usually require (1) synthesis and mass production of a release strain genetically different from the target population, (2) survival of the release strain in the field and successful mating with the target population, and (3) transmission of the new genetic material through several generations. Although the first two criteria have been met for some vectors of human disease (Laven et al, 1972;Grover et al, 1976;Petersen et al, 1977;McDonald et al, 1977;Lorimer et al, 1976), tests of genetic control to date have supplied little evidence for step 3, continuous inheritance of introduced genes (Hausermann et al, 1971;Rai et al, 1973). The transmission of introduced genetic markers within a Kenya population of Aedes aegypti (L.) for 49 weeks after the end of releases is reported in this paper.…”

Sex separation ofAedesspp. mosquitoes for sterile insect technique application: a review

“…After the first successful case of the SIT used against the screw worm Cochiomyia homnivorax (Coquerel) in 1954, application of the SIT has been extended to other pests of agricultural or public health interest (Dyck et al, 2021), such as mosquito vectors of diseases. Early attempts to establish programs of release of sterile mosquitos have taken place since the 1950s with the genera Culex (Laven, 1967(Laven, , 1971Laven & Aslamkhan, 1970;Patterson et al, 1970;Grover et al, 1976;Curtis et al, 1982), Anopheles (Weidhaas et al, 1962(Weidhaas et al, , 1974Davidson et al, 1970;Bailey et al, 1980), andAedes (McDonald et al, 1977;Petersen et al, 1977).…”