Multi-loop Feynman integrals are key objects for the high-order correction computations in high energy phenomenology. These integrals with multiple scales may have complicated symbol structures, and we show that twistor geometries of closely related dual conformal integrals shed light on their alphabet and symbol structures. In this paper, first, as a cutting-edge example, we derive the two-loop four-external-mass Feynman integrals with uniform transcendental (UT) weights, based on the latest developments on UT integrals. Then we find that all the symbol letters of these integrals can be explained non-trivially by studying the so-called Schubert problem of certain dual conformal integrals with a point at infinity. Certain properties of the symbol such as first two entries and extended Steinmann relations are also studied from analogous properties of dual conformal integrals.