Fifteen-Month Lifestyle Intervention Program to Improve Cardiovascular Risk Factors in a Community Population in Japan

Exercise Differentially Regulates Renalase Expression in Skeletal Muscle and Kidney

“…After prolonged training, heart rate is decreased, and blood pressure is lowered, in comparison to the pre-training period (Kokkinos et al 2009). The average training-related reduction in blood pressure differs between investigated groups, and depends on many factors, including the intensity, duration, and type of training (Haruyama et al 2009;Manfredini et al 2009;Chen et al 2010). In normotensive groups, the mean decrease in resting systolic and diastolic blood pressure after endurance training was 3 mmHg and 2.4 mmHg, respectively (Fagard 2006).…”

Community-Based Lifestyle Modification of Cardiovascular Disease Risks in Middle-Aged Japanese: A 27-Month Update

“…Details of the project in the present study have been reported previously (Haruyama et al 2009). The lifestyle intervention program was designed by local community health workers in Soka city based on the "Health-Up Model Project" by the Ministry of Health, Labour and Welfare of Japan (Haruyama et al 2009).…”

“…In a Japanese community, the use of existing health examination in community health services as a basis for lifestyle intervention programs is considered one of the most feasible methods (Egawa et al 2004). Several trials in community settings have demonstrated the effect of lifestyle interventions targeting a middle-aged community-dwelling population for the reduction of obesity (Mitsuhashi et al 2003;Noda et al 2006;Egawa et al 2007), hypertension (Iso et al 1996;Miura et al 2006), diabetes (Kuriyama et al 2006), dyslipidemia (Amano et al 2002;Iso et al 2002) and risk of cardiovascular diseases (Haruyama et al 2009). Using data of the same cohort as the present study, Haruyama et al (2009) found that there was a significant mean weight reduction and increase of physical activity in a lifestyle intervention group compared with a control group for 15 months among males and females.…”

“…Several trials in community settings have demonstrated the effect of lifestyle interventions targeting a middle-aged community-dwelling population for the reduction of obesity (Mitsuhashi et al 2003;Noda et al 2006;Egawa et al 2007), hypertension (Iso et al 1996;Miura et al 2006), diabetes (Kuriyama et al 2006), dyslipidemia (Amano et al 2002;Iso et al 2002) and risk of cardiovascular diseases (Haruyama et al 2009). Using data of the same cohort as the present study, Haruyama et al (2009) found that there was a significant mean weight reduction and increase of physical activity in a lifestyle intervention group compared with a control group for 15 months among males and females. Though most of these studies evaluated programs lasting 3 to 18 months and showed improvements in each target risk (Iso et al 1996Amano et al 2002;Mitsuhashi et al 2003;Kuriyama et al 2006;Miura et al 2006;Noda et al 2006;Egawa et al 2007), the effect of lifestyle intervention programs for two years or longer in Japanese community settings have not yet been clarified.…”

“…The present study investigated whether a long-term intervention program conducted by local community health workers targeting a high risk population in a community setting could achieve desirable effects on lifestyle behaviors and cardiovascular disease risks at 27 months on further follow-up of subjects from the previous study (Haruyama et al 2009). …”