“…26,27 Percutaneous transluminal coronary angioplasty alone or together with implantable stents is now the most commonly used approach for treating occlusive coronary artery disease. 28 Restenosis, however, limits the longterm success of percutaneous transluminal coronary angioplasty, necessitating second procedures or coronary bypass surgery. Intimal hyperplasia, because of smooth muscle cell proliferation and migration, is thought to be a major cause of restenosis 17 and may also play an important role in the progression of atherosclerotic plaques.…”