CPPU) is one of the plant growth regulators (PGRs) used to enhance tree yield and quality, as well as to enhance late fig fruit yield and its quality. The aim of this study was to study the influences of CPPU foliar application on growth, physio-biochemical attributes, nutritional homeostasis, and late fruit quality of fig trees under late season conditions (leaf senescence and low temperature). Fig trees sprayed three times with 40.0 µM CPPU showed the best growth (average leaf dry weight and dry matter content), late fruit yield (fruit number branch -1 and average fruit weight), and fruit quality traits (contents of fruit total soluble sugars, total soluble solids, and vitamin C) due to enhancements in chlorophyll biosynthesis, relative water content, total soluble sugars, and nutrient balance. These findings recommend the use of three foliar sprays of 40.0 µM CPPU application to promote late fig fruit yield and its quality.