Film and pharmaceutical hard capsule formation properties of mungbean, waterchestnut, and sweet potato starches

Bae, Hojae; Dong, Shihua; Whiteside, William Scott; Park, Hyun J.

doi:10.1016/j.foodchem.2007.05.070

Cited by 107 publications

(66 citation statements)

References 23 publications

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“…Soft capsules have strengths of less than 1 MPa, which can be reduced by swelling with the contents, [151] while hard gelatin has a strength of about 20 MPa. [152] There is interest in replacing gelatin with starch or other biodegradable polymers, but matching the strength and swelling properties of gelatin has been a barrier. [152,153] There is much interest in developing transdermal drug delivery as an alternative to oral routes.…”

Section: Drug-delivery Systemsmentioning

confidence: 99%

Hydrogels for Soft Machines

2009

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Hydrogels have applications in surgery and drug delivery, but are never considered alongside polymers and composites as materials for mechanical design. This is because synthetic hydrogels are in general very weak. In contrast, many biological gel composites, such as cartilage, are quite strong, and function as tough, shock‐absorbing structural solids. The recent development of strong hydrogels suggests that it may be possible to design new families of strong gels that would allow the design of soft biomimetic machines, which have not previously been possible.

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Section: Drug-delivery Systemsmentioning

confidence: 99%

Hydrogels for Soft Machines

2009

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“…Among the polysaccharides, starch is the most widely used in the elaboration of films, due to its low cost and abundance in nature [1]. Starch and starch derivative films have been widely studied due to their great molding and film-forming properties, high oxygen barrier, and good mechanical strength [2,3].…”

Section: Introductionmentioning

confidence: 99%

“…In a previous study, biodegradable films were developed using starches from different plant sources as the base raw materials such as sweet potato [2], yam [3][4][5], corn [6], potato [7], cassava [8][9][10], rice [11], and sago [12,13]. Moreover, sugar palm starch is also a potential biopolymer material for making biodegradable films [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Mechanical and microstructural properties of sugar palm (Arenga pinnata Merr.) starch film: Effect of aging

Apriyana¹,

Poeloengasih²,

Hernawan³

et al. 2016

AIP Conference Proceedings

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A physicochemical study of sugar palm (Arenga Pinnata) starch films plasticized by glycerol and sorbitol AIP Conference Proceedings 1711, 080003 (2016) (20, 30, 40 and 50% w/w starch). The film samples were stored for 1, 4 and 8 week at 25 o C under 52%RH. The results showed that there is an increasing tendency of thickness, moisture content, solubility, and elongation at break as glycerol concentration increased, whereas tensile strength decreased as glycerol concentration were raised. The moisture content and solubility of plasticized film initially increased after 1 week but decreased after 4 weeks of storage. Aging films affected to mechanical properties, increasing resistance but reducing their stretchability. The XRD results showed that the crystallinity of sample with various glycerol concentration tends to decrease after 8 weeks storage.

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“…A method by Bae et al [3] was adopted with some modifications. An amount of glycerol or sorbitol (30, 35, 40, 45 and 50% w/w starch) was dispersed in water and maintained under continuous agitation at 50°C for 30 min.…”

Section: Film-forming Solution Preparationmentioning

confidence: 99%

“…Many researchers have investigated and developed natural substances from vegetal sources into medical capsule material. Numerous natural polysaccharides have also been investigated for their potentials to replace gelatin [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

A physicochemical study of sugar palm (Arenga Pinnata) starch films plasticized by glycerol and sorbitol

Poeloengasih¹,

Pranoto²,

Hayati³

et al. 2016

AIP Conference Proceedings

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Abstract.The present work explores the physicochemical characteristics of sugar palm starch film for a potential hard capsule purpose. Sugar palm (Arenga pinnata) starch films were plasticized with glycerol or sorbitol in various concentrations (30% up to 50% w/w starch). Their effects on physicochemical properties of the films were investigated. The results showed that sugar palm starch was successfully developed as the main material of film using casting method. Incorporation of both glycerol or sorbitol affected the properties of films in different ways. It was found that thickness and solubility increased as plasticizer concentration increased, whereas retraction ratio, swelling degree and swelling thickness decreased with the increased plasticizer concentration.

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Film and pharmaceutical hard capsule formation properties of mungbean, waterchestnut, and sweet potato starches

Cited by 107 publications

References 23 publications

Hydrogels for Soft Machines

Hydrogels for Soft Machines

Mechanical and microstructural properties of sugar palm (Arenga pinnata Merr.) starch film: Effect of aging

A physicochemical study of sugar palm (Arenga Pinnata) starch films plasticized by glycerol and sorbitol

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