Films composed of white angico gum and chitosan containing chlorhexidine as an antimicrobial agent

Oliveira, Roger Wallacy Guimarães; Oliveira, Jefferson Magalhães de; Paz, Francyellen Batista da; Muniz, Edvani C.; Moura, Edmílson Miranda de; Costa, Juliana Leles; Nascimento, Matheus Oliveira do; Carvalho, André Luís Menezes; Pinheiro, Iluska Martins; Mendes, Anderson Nogueira; Filgueiras, Lívia Alves; Souza, Paulo Ricardo Martins; Moura, Carla Verônica Rodarte de

doi:10.1016/j.ijbiomac.2023.123905

Cited by 7 publications

(1 citation statement)

References 72 publications

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“…Thus, apparently, the biocompatibility of AcG seems to be superior to that of other natural gums that have already been extensively studied, such as Karaya and Chichá gums (extracted from the genus Sterculia), which demonstrated hemolysis below 1% at the concentrations evaluated (100.0 to 0.78 μg/mL) [45] . Or even White Angico gum (Anadenanthera colubrina), which exhibited a hemolysis rate close to 2% at all concentrations tested (10 to 1000 μg/mL) [46] . In the work of Quelemes et al [22] , cashew gum (Anacardium occidentale) promoted approximately 10% hemolysis at a 1000 μg/mL concentration.…”

Section: Hemolytic Assaymentioning

confidence: 96%

Polysaccharide from Cumaru (Amburana cearensis) exudate and its potential for biotechnological applications

Silva,

Araújo,

Silva

et al. 2024

Polímeros

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Amburana cearensis tree is used in various applications, from artisanal to pharmaceutical use. However, the gum extracted from its exudate has not yet been investigated. This study aimed to the physicochemical and structural characterization of Amburana cearensis Gum (AcG) by elemental, rheological, and thermal analyses, X-ray diffraction (XRD), high-Performance Liquid Chromatography (HPLC), Gel Permeation Chromatography (GPC), Infrared Spectroscopy (FTIR), UV-Vis spectroscopy and nuclear magnetic resonance (NMR). Additionally, a hemolytic assay was performed to evaluate the biocompatibility of AcG using human erythrocytes. The results showed that AcG consists of β-D-Galactopyranose monomers linked by glycosidic bonds (1→3). At the same time, the side chains exhibit β-Galactopyranose (1→6) and α-L-Arabinofuranoside (1→3,6) monomers as non-reducing terminals, whose biocompatibility was excellent in the model used. AcG was described for the first time as a biopolymer that could have broad applications in the pharmaceutical and cosmetic industries, justifying the interest in further studies about AcG applications.

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Section: Hemolytic Assaymentioning

confidence: 96%

Polysaccharide from Cumaru (Amburana cearensis) exudate and its potential for biotechnological applications

Silva,

Araújo,

Silva

et al. 2024

Polímeros

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Composition of Sodium Alginate Films Containing Copper Oxide Nanoparticles Synthesized Using Aqueous Extract of Turnera subulata Sm and Evaluation of Their Healing Potential In Vivo

Alves Batista,

Raulino Maia,

Martins Maia Filho

et al. 2024

Journal of Polymer Science

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Sodium alginate is used in wound care because of its hydrogel‐forming properties and ability to protect the wound. Copper nanoparticles have properties that inhibit the growth of microorganisms and mediate the production of essential biomolecules for the healing process, making them an excellent choice for constructing nanocomposites for wound treatment. This work aimed to synthesize copper nanoparticles using an aqueous extract of Turnera subulata Sm. and incorporate them into sodium alginate to obtain films with healing potential. The proposed system was characterized by ultraviolet–visible spectroscopy (UV–vis), Fourier‐transform infrared (FTIR), dynamic light scattering (DLS), atomic force microscopy (AFM), x‐ray crystallography, and biocompatibility verified by hemolysis test. The UV–vis analysis showed that CuO NPs absorb at 280 and 404 nm. The FTIR spectra revealed stretching and folding modes of the functional groups present in the aqueous extract of T. subulata responsible for the reduction/stabilization of the copper ion, as well as signals at 780 and 618 cm−1 originating from the CuO bond. Size estimation using DLS revealed 564.5 and 394.2 nm. AFM data showed that adding copper oxide nanoparticles (CuO NPs) changed alginate roughness, and surface imaging revealed a material with a uniform appearance. The hemolysis test showed hemocompatibility of CuO NPs at all tested concentrations. Histology showed that CuONP‐loaded alginate films accelerated the healing process.

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Biopolymer from the Puree of Mesocarp of Citrullus lanatus (Watermelon) Containing Chlorhexidine Digluconate: Physical-Chemistry Characterization and Biological Aspects

Paris Junior,

Nogueira,

Cerqueira

et al. 2024

Waste Biomass Valor

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Films composed of white angico gum and chitosan containing chlorhexidine as an antimicrobial agent

Cited by 7 publications

References 72 publications

Polysaccharide from Cumaru (Amburana cearensis) exudate and its potential for biotechnological applications

Polysaccharide from Cumaru (Amburana cearensis) exudate and its potential for biotechnological applications

Composition of Sodium Alginate Films Containing Copper Oxide Nanoparticles Synthesized Using Aqueous Extract of Turnera subulata Sm and Evaluation of Their Healing Potential In Vivo

Biopolymer from the Puree of Mesocarp of Citrullus lanatus (Watermelon) Containing Chlorhexidine Digluconate: Physical-Chemistry Characterization and Biological Aspects

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