Purpose: of the article is to study the existing system of state financial support for small and medium-sized enterprises (SMEs) in the Tyumen Oblast in order to identify problematic points of SME development in the region and determine of appropriate measures for their adjustment.Methods: in the part of the study on the quantitative indicators of State financial support for SMEs, statistical analysis was used, including a study of the structure and dynamics of measures implemented, as well as the number of SMEs. To assess the degree of influence of the tools used on the development of SMEs, data from the ongoing program of state financial support in the Tyumen Oblast were used.Results: in the course of the research, the main determinants constraining the effectiveness of the use of State financial support tools for SMEs in the Tyumen Oblast were identified. The lack of systematic and comprehensive State financial support for SMEs was revealed, which would reflect the vision of the elements of the system and the establishment of the relationships between them, taking into account changes in the external environment and the indication of the most effective support measures for individual areas of SMEs activity.Сonclusions and Relevance: as a result of the study, the need to modernize the implemented state financial support for SMEs in the Tyumen Oblast in the direction of expanding the list of instruments and diversifying the measures applied to legal entities and individual entrepreneurs has been established. As one of the promising areas, it seems reasonable to create guaranteed sales markets and active connection of SMEs to business networks. This will maximize the effectiveness of measures applied to support economically and socially important SMEs, taking into account their specifics, strengthen the financial condition of enterprises in this sector and thus ensure the stability of the economic development of the region.