Financial Impact of Failing to Prevent Surgical Site Infections

Sparling, Karen W.; Ryckman, Frederick C.; Schoettker, Pamela J.; Byczkowski, Terri; Helpling, Alma; Mandel, Keith E.; Panchanathan, Anitha; Kotagal, Uma R.

doi:10.1097/01.qmh.0000281058.99929.ea

Cited by 93 publications

(65 citation statements)

References 17 publications

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“…Although some results are inconclusive, two meta-analyses concluded that vancomycin resistance is associated with greater rates of clinical treatment failure and recurrence, and higher all-cause mortality than infections with susceptibile enterococci. [92,93] The 2005 study by DiazGranados and colleagues concluded that patients with bacteraemia caused by VRE were more likely to die than those with vancomycin-sensitive enterococcal bacteraemia, with a summary odds ratio of 2.52 (95%CI, 1.9 to 3.4). [93] …”

Section: Harm To Patients From Vancomycin-resistant Enterococcimentioning

confidence: 99%

“…[92,93] The 2005 study by DiazGranados and colleagues concluded that patients with bacteraemia caused by VRE were more likely to die than those with vancomycin-sensitive enterococcal bacteraemia, with a summary odds ratio of 2.52 (95%CI, 1.9 to 3.4). [93] …”

Section: Harm To Patients From Vancomycin-resistant Enterococcimentioning

confidence: 99%

“…[89] Internationally, widespread use of fluoroquinolone prophylaxis for neutropenic patients has been associated with the emergence of resistant gram-negative isolates. [90,91] The emergence of resistant bacterial isolates -including vancomycin-resistant enterococci (VRE), [92] MRSA [93] and multiresistant gram-negative organisms [92] -is likely to have happened at the same time as the circulation of endemic and outbreak strains within non-haematology populations in individual health-care institutions.…”

Section: Haematology-oncology Patientsmentioning

confidence: 99%

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Characterising health care‐associated bloodstream infections in public hospitals in Queensland, 2008–2012

Runnegar

Marquess

et al. 2016

Medical Journal of Australia

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Objective: To describe the epidemiology and rates of all health care‐associated bloodstream infections (HA‐BSIs) and of specific HA‐BSI subsets in public hospitals in Queensland. Design and setting: Standardised HA‐BSI surveillance data were collected in 23 Queensland public hospitals, 2008–2012. Main outcome measures: HA‐BSIs were prospectively classified in terms of place of acquisition (inpatient, non‐inpatient); focus of infection (intravascular catheter‐associated, organ site focus, neutropenic sepsis, or unknown focus); and causative organisms. Inpatient HA‐BSI rates (per 10 000 patient‐days) were calculated. Results: There were 8092 HA‐BSIs and 9418 causative organisms reported. Inpatient HA‐BSIs accounted for 79% of all cases. The focus of infection in 2792 cases (35%) was an organ site, intravascular catheters in 2755 (34%; including 2240 central line catheters), neutropenic sepsis in 1063 (13%), and unknown in 1482 (18%). Five per cent (117 of 2240) of central line‐associated BSIs (CLABSIs) were attributable to intensive care units (ICUs). Eight groups of organisms provided 79% of causative agents: coagulase‐negative staphylococci (18%), Staphylococcus aureus (15%), Escherichia coli (11%), Pseudomonas species (9%), Klebsiella pneumoniae/oxytoca (8%), Enterococcus species (7%), Enterobacter species (6%), and Candida species (5%). The overall inpatient HA‐BSI rate was 6.0 per 10 000 patient‐days. The rates for important BSI subsets included: intravascular catheter‐associated BSIs, 1.9 per 10 000 patient‐days; S. aureus BSIs, 1.0 per 10 000 patient‐days; and methicillin‐resistant S. aureus BSIs, 0.3 per 10 000 patient‐days. Conclusions: The rate of HA‐BSIs in Queensland public hospitals is lower than reported by similar studies elsewhere. About one‐third of HA‐BSIs are attributable to intravascular catheters, predominantly central venous lines, but the vast majority of CLABSIs are contracted outside ICUs. Different sources of HA‐BSIs require different prevention strategies.

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Section: Harm To Patients From Vancomycin-resistant Enterococcimentioning

confidence: 99%

Section: Harm To Patients From Vancomycin-resistant Enterococcimentioning

confidence: 99%

Section: Haematology-oncology Patientsmentioning

confidence: 99%

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Characterising health care‐associated bloodstream infections in public hospitals in Queensland, 2008–2012

Runnegar

Marquess

et al. 2016

Medical Journal of Australia

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“…In North America, one fourth of hospital-acquired infections are SSI, resulting in billions of dollars in hospitalization costs annually; therefore, major efforts are concentrated on prevention [3][4][5]. A considerable proportion of infants admitted to the neonatal intensive care unit (NICU) require surgical interventions.…”

Section: Introductionmentioning

confidence: 99%

Surgical site infections in infants admitted to the neonatal intensive care unit

Segal¹,

Kang

Albersheim

et al. 2014

Journal of Pediatric Surgery

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“…2012; 46(6):1483-92 www.ee.usp.br/reeusp/ A systematic review of surgical hand antisepsis utilizing an alcohol preparation compared to traditional products Gonçalves KJ, Graziano KU, Kawagoe JY intRodUction Surgical site infections are the major cause of postoperative morbidity and mortality and represent large costs to hospitals (1) . In spite of the multifactorial cause, molecular biology-based studies have correlated the surgical site infections to the surgical team's hand surgical antisepsis, which may even include outbreaks (2)(3)(4) .…”

Section: Rev Esc Enferm Uspmentioning

confidence: 99%

Revisão sistemática sobre antissepsia cirúrgica das mãos com preparação alcoólica em comparação aos produtos tradicionais

Gonçalves¹,

Graziano

Kawagoe³

2012

Rev. esc. enferm. USP

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A antissepsia cirúrgica das mãos visa à prevenção de infecções do sítio cirúrgico, importante causa de morbimortalidade pós-operatória e aumento dos custos hospitalares. Este estudo teve como objetivo comparar a eficácia de preparações alcoó-licas com os produtos tradicionais na antissepsia cirúrgica das mãos por meio de uma revisão sistemática da literatura. Foram considerados estudos primários ou secundários, tendo como desfecho a contagem microbiana das mãos ou taxas de infecções do sítio cirúrgico. A busca foi realizada no Portal BVS, PubMed, Ask e MEDLINE. Foram selecionados 25 estudos (2 revisões sistemáticas, 19 experimentais e 4 de corte). As preparações alcoólicas tiveram uma redução microbiana igual e/ou maior aos produtos tradicionais em 17 estudos e inferior em 4; as taxas de infecções do sítio cirúrgico foram similares. Portanto, existem evidências científicas que suportam a segurança das preparações alcoólicas para antissepsia cirúrgica das mãos. dEScRitoRES Antissepsia Cirurgia geral Lavagem de mãos Controle de infecções Enfermagem de Centro CirúrgicoA systematic review of surgical hand antisepsis using an alcohol preparation compared to traditional products * Original article AbStRActSurgical hand antisepsis aims at preventing surgical site infections, an important cause of postoperative morbidity and mortality and escalating hospital costs. The objectives of this study were to compare the efficacy of alcohol preparations with traditional surgical hand antisepsis products by means of a systematic review of the literature. Primary and secondary studies were included, considering the microbial count or surgical site infection rates as outcomes. The search was performed on the BVS Portal, PubMed, Ask and MEDLINE. Twentyfive studies were selected (two systematic reviews, nineteen experimental and four cohort studies). The alcohol preparations promoted a microbial reduction equal to and/or greater than traditional products in 17 studies, and a lesser reduction in four studies; similar surgical site infection rates were identified. Therefore, there is scientific evidence that support the safety of alcohol preparations for surgical hand antisepsis. RESUmEnLa antisepsia quirúrgica de manos apunta a prevenir infecciones en el sitio quirúrgi-co, causa importante de morbi-mortalidad postoperatoria y aumento de costos hospitalarios. El estudio objetivó comparar la eficacia de preparaciones alcohólicas con los productos tradicionales de la antisepsia quirúrgica de manos, mediante revisión sistemática de la literatura. Fueron considerados estudios primarios o secundarios, teniendo como objetivo el recuento microbiano en manos o tasas de infecciones del sitio quirúrgico. La búsqueda fue realizada en las bases BVS, PubMed, Ask y MEDLINE. Fueron seleccionados 25 estudios (2 revisiones sistemáticas, 19 experimentales y 4 de cohorte). Las preparaciones alcohólicas consiguieron una reducción microbiana igual y/o mayor que los productos tradicionales en 17 estudios, e inferior en 4; las tasas de infección del sitio ...

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Financial Impact of Failing to Prevent Surgical Site Infections

Cited by 93 publications

References 17 publications

Characterising health care‐associated bloodstream infections in public hospitals in Queensland, 2008–2012

Characterising health care‐associated bloodstream infections in public hospitals in Queensland, 2008–2012

Surgical site infections in infants admitted to the neonatal intensive care unit

Revisão sistemática sobre antissepsia cirúrgica das mãos com preparação alcoólica em comparação aos produtos tradicionais

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