The results of the 2022 research devoted to the records and spread of invasive plant species within the Orenburg region, which will become the basis for the Black Book of Flora of the Orenburg region, © Голованов Я. М., Абрамова Л. М., 2023 БИОЛОГИЧЕСКИЕ НАУКИ / BIOLOGICAL SCIENCES Вестник Оренбургского государственного педагогического университета Электронный научный журнал (online). ISSN 2303-9922. http://vestospu.ru 2023. № 1 (45) 7 are presented. 194 localities of 20 invasive and potentially invasive plant species were identified on the territory of the south-western districts of the Orenburg region. Of these, 6 species belong to 1 invasive status: transformer species that are actively introduced into natural and semi-natural communities (Ambrosia trifida, Bidens frondosa, Echinocystis lobata, Elaeagnus angustifolia, Iva xanthiifolia, Xanthium albinum); 1 species belongs to the second invasive status: these are species actively introduced in disturbed semi-natural and natural habitats (Lepidium draba); 12 species belong to the third invasive status: species actively introduced in disturbed habitats (Amaranthus albus, A. blitoides, Bassia scoparia, Bromus squarrosus, B. tectorum, Centaurea diffusa, Grindelia squarrosa, Lepidium densiflorum, Onopordum acanthium, Portulaca oleracea, Rhaponticum repens, Sisymbrium volgense); 1 potentially invasive species belonging to the fourth invasive status. One species Rhaponticum repens is quarantine. A high species diversity of the invasive component of the flora of the south-western districts of Orenburg region was noted.