Findings significant with respect to short- and medium-term outcome in schizophrenia —A preliminary report

Straube, Eckart R.; Wagner, Wolfgang; Foerster, Klaus; Heimann, H

doi:10.1016/0278-5846(89)90016-x

Cited by 20 publications

(9 citation statements)

References 16 publications

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“…While 29 of the 37 patients with cardiac problems were depressed, 15 -----same as the total sample. We did not test some of the variables in the literature (such as orientation and nature of psychotic phase (6), stimulus barrier (7), and premorbid personality (1)). Clearly more work is needed.…”

Section: Discussionmentioning

confidence: 99%

“…For schizophrenic patients the support system predictors of remission are: low levels of family expressed emotion (3), non-familial social resources and low level of family involvement (4) and positive attitude of relatives and neighbors (1). The clinical predictors of remission for schizophrenic patients are: positive syndrome (9, confusion, disorientation and perplexity at height of psychotic phase (6), low stimulus barrier (7), nonschizoid premorbid personality (l), non-impaired social functioning (8) and short duration of illness prior to admission (1,9). The treatment factors predicting remission are: compliance with medication (1) and good response to haloperidol (9).…”

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confidence: 99%

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Understanding who improves after psychiatric hospitalization

Rabinowitz

Modai

Inbar-Saban

1994

Acta Psychiatr Scand

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Rabinowitz J, Modai I, Inbar-Saban N . Understanding who improves after psychiatric hospitalization. Acta Psychiatr Scand 1994: 89: 152-158. 0 Munksgaard 1994.This study attempts to identify variables associated with improved functioning after psychiatric hospitalization. The relationship between 25 clinical and demographic variables and improvements and functioning at discharge of 309 consecutive patients in an open ward over 2 years were studied using stepwise logistic regression. Measures of patient functioning at discharge were score above or below 50 on the (Global Assessment of Functioning scale) (GAF) and 3-point scale of functioning 1 week after discharge (needs constant supervision, functions independently at home, functions on the job). We created a logistic regression model of outcome based on the information available at admission and one based also on information at time of discharge (i.e., medication, therapy and length of stay etc.). Discharge models predicted 6-10% better than admission models. Discharge models correctly predicted whether G A F level was above 50 in 72"/, of the cases and return to preadmission functioning in 71We also created a model of functioning at discharge using a hierarchical logistic regression model. It correctly predicted 7404 of the lowest level of functioning, 47% of the middle level and 68% of the highest level. The best predictors of improved functioning after discharge were preadmission levels of functioning, psychotherapy in hospital, absence of organic brain syndrome, attendance at occupational therapy and hospitalization less than 4 months. Diagnosis had almost no discernible effect on outcome of of the cases.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Understanding who improves after psychiatric hospitalization

Rabinowitz

Modai

Inbar-Saban

1994

Acta Psychiatr Scand

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“…However, as is often the case in research on schizophrenia, there also is a pattern of findings suggesting an opposite conclusion: that a high level of electrodermal activity is related to the severity of schizophrenic illness. A highly reactive SCR pattern has been found to be related to poor symptomatic outcome in several independent studies (Dawson, Nuechterlein, Schell, & Mintz, 1992;Frith, Stevens, Johnstone, & Crow, 1979;Straube, Wagner, Foerster, & Heiman, 1989;Wieselgren, Ohlund, Lindstrom, & Ohman, 1994;Zahn, Carpenter, & McGlashan, 1981).…”

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confidence: 97%

Electrodermal activity and social network as predictors of outcome of episodes in schizophrenia.

Hultman

Ls²,

Im³

et al. 1996

Journal of Abnormal Psychology

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The predictive value of electrodermal activity and social network was examined among 48 consecutively admitted schizophrenic patients. The patients were followed from an initial admission, through hospital stay, discharge, follow-up (M = 31 months), and possible relapse. Outcome variables were the length of stay in the hospital at the key episode and time to relapse, defined as a marked exacerbation or return of schizophrenic symptoms requiring inpatient or expansion of outpatient treatment. Multivariate analyses showed that a psychosocial variable, the availability of attachment, was the only independent predictor of length of stay in the hospital. Age at admission was a strong predictor of time to relapse. Age interacted with both outcome and electrodermal activity, and young electrodermal nonresponders were found to have the shortest time to relapse. At the 1-year follow-up, a main relapse effect was found for patients with a low skin conductance level.

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“…However, other investigators have found that higher levels of electrodermal activity were concurrently associated with higher levels of symptoms or longer hospital stays in schizophrenia (Frith, Stevens, Johnstone, & Crow, 1979;Straube, Wagner, Foerster, & Heiman, 1989;Zahn, Carpenter, & McGlashan, 1981). In more recent studies, Fuentes et al (1993), in addition to finding that negative symptoms were concurrently greater among nonresponders, also found that some positive symptoms were greater among responders.…”

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Electrodermal predictors of functional outcome and negative symptoms in schizophrenia

et al. 2005

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The ability of electrodermal variables to predict negative symptoms and functional outcome over a 1-year period in schizophrenia was investigated in 78 young, recent-onset outpatients. Patients were stabilized on standardized medication and largely free of psychotic symptoms. Higher levels of both tonic (skin conductance level, nonspecific skin conductance response rate) and phasic (number of skin conductance orienting responses) activity were associated with more negative symptoms and with a combination of poorer social and occupational outcome at 1-year follow-up. This pattern was seen in both male and female patients, and in older and younger patients. Results are interpreted as suggesting that high levels of arousal and overreactivity to the environment may interfere with efficient cognitive processing in schizophrenia, contributing to poor outcome, and that negative symptoms might partially serve as a means of coping with overarousal.

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Findings significant with respect to short- and medium-term outcome in schizophrenia —A preliminary report

Cited by 20 publications

References 16 publications

Understanding who improves after psychiatric hospitalization

Understanding who improves after psychiatric hospitalization

Electrodermal activity and social network as predictors of outcome of episodes in schizophrenia.

Electrodermal predictors of functional outcome and negative symptoms in schizophrenia

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