Fine Motor Function Skills in Patients with Parkinson Disease with and without Mild Cognitive Impairment

Dahdal, Philippe; Meyer, Antonia; Chaturvedi, Menorca; Nowak, Karolina; Roesch, Anne Dorothée; Fuhr, Peter; Gschwandtner, Ute

doi:10.1159/000448751

Cited by 30 publications

(27 citation statements)

References 31 publications

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“…is assumption concurs with the finding of impaired dexterity in Parkinson's disease, predominantly in advanced stages of the disease [8]. Furthermore, a recent study proved that fine motor skills in Parkinson's disease patients are impaired, predominantly in patients with mild cognitive impairment [42]. Probably, at a certain, difficult to predict stage of Parkinson's disease, patients become dependent on professional or voluntary care providers for proper daily oral hygiene care.…”

Section: Discussionsupporting

confidence: 82%

Oral health of Parkinson’s disease patients, a case-control study

Baatt¹,

Stiphout²,

Marinus

et al. 2018

Parkinsonism & Related Disorders

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e aim of the study was to examine the oral health status of Parkinson's disease (PD) patients, to compare their oral health status to that of a control group, and to relate it to the duration and severity of PD. Materials and Methods. 74 PD patients and 74 controls were interviewed and orally examined. Among PD patients, the duration and the Hoehn and Yahr stage (HY) of the disease were registered. Results. More PD patients than controls reported oral hygiene care support as well as chewing/biting problems, taste disturbance, tooth mobility, and xerostomia, whereas dentate patients had more teeth with carious lesions, tooth root remnants, and biofilm. Both longer duration and higher HY were associated with more chewing problems and, in dentates, more teeth with restorations. In dentates, longer duration of the disease was associated with higher number of mobile teeth. Higher HY was associated with more oral hygiene care support as well as biting problems and, in dentates, more teeth with carious lesions and tooth root remnants. Conclusions. Comparatively, PD patients had weakened oral health status and reduced oral hygiene care. Both duration and severity of the disease were associated with more oral health and hygiene care problems.

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Section: Discussionsupporting

confidence: 82%

Oral health of Parkinson’s disease patients, a case-control study

Baatt¹,

Stiphout²,

Marinus

et al. 2018

Parkinsonism & Related Disorders

View full text Add to dashboard Cite

show abstract

“…This assumption concurs with the finding of impaired dexterity in Parkinson's disease, predominantly in advanced stages of the disease [ 8 ]. Furthermore, a recent study proved that fine motor skills in Parkinson's disease patients are impaired, predominantly in patients with mild cognitive impairment [ 42 ]. Probably, at a certain, difficult to predict stage of Parkinson's disease, patients become dependent on professional or voluntary care providers for proper daily oral hygiene care.…”

Section: Discussionmentioning

confidence: 99%

Oral Health of Parkinson’s Disease Patients: A Case-Control Study

Stiphout¹,

Marinus

Hilten

et al. 2018

Parkinson's Disease

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The aim of the study was to examine the oral health status of Parkinson's disease (PD) patients, to compare their oral health status to that of a control group, and to relate it to the duration and severity of PD. Materials and Methods. 74 PD patients and 74 controls were interviewed and orally examined. Among PD patients, the duration and the Hoehn and Yahr stage (HY) of the disease were registered. Results. More PD patients than controls reported oral hygiene care support as well as chewing/biting problems, taste disturbance, tooth mobility, and xerostomia, whereas dentate patients had more teeth with carious lesions, tooth root remnants, and biofilm. Both longer duration and higher HY were associated with more chewing problems and, in dentates, more teeth with restorations. In dentates, longer duration of the disease was associated with higher number of mobile teeth. Higher HY was associated with more oral hygiene care support as well as biting problems and, in dentates, more teeth with carious lesions and tooth root remnants. Conclusions. Comparatively, PD patients had weakened oral health status and reduced oral hygiene care. Both duration and severity of the disease were associated with more oral health and hygiene care problems.

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“…The effects of tDCS over M1 on hand dexterity we so far less explored, with a previous report suggesting that it does not improve hand dexterity in PD patients (Fregni et al, 2006 ). It has been suggested that dexterity or fine motor control of the hand could be used to assess severity of PD (Pradhan et al, 2010 ; Dahdal et al, 2016 ). The present results along with these previous studies suggest that tDCS over the FPA could be useful alternative treatment of PD.…”

Section: Discussionmentioning

confidence: 99%

Effects of Transcranial Direct Current Stimulation (tDCS) Over the Frontal Polar Area on Motor and Executive Functions in Parkinson’s Disease; A Pilot Study

Ishikuro

Dougu

Nukui

et al. 2018

Front. Aging Neurosci.

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Parkinson’s disease (PD) is a neurodegenerative disorder with motor and non-motor symptoms due to degeneration of dopaminergic neurons. The current pharmacological treatments induce complications associated with long-term use. However, current stimulation techniques for PD treatment, such as deep brain stimulation (DBS), are too invasive. In this context, non-invasive brain stimulation including transcranial direct current stimulation (tDCS) may be a safe and effective alternative treatment for PD. We previously reported that anodal tDCS over the frontal polar area (FPA) improved motor functions in heathy subjects. Therefore, in the present study, effects of tDCS over the FPA on motor and cognitive functions of PD patients were analyzed. Nine PD patients (3 men and 6 women) participated in this cross over study with three tDCS protocols; anodal, cathodal or sham tDCS over the FPA. Each tDCS protocol was applied for 1 week (5 times/week). Before and after each protocol, motor and cognitive functions of the patients were assessed using Unified PD Rating Scale [UPDRS (part III: motor examination)], Fugl Meyer Assessment set (FMA), Simple Test for Evaluating hand Function (STEF) and Trail Making Test A (TMT-A). The results indicated that anodal stimulation significantly decreased scores of motor disability in UPDRS-III compared with sham and cathodal stimulation, and significantly increased scores of motor functions in FMA compared with sham stimulation. Furthermore, anodal stimulation significantly decreased time to complete a motor task requiring high dexterity in STEF compared with those requiring low and medium levels of dexterity. In addition, anodal stimulation significantly decreased time to complete the TMT-A task, which requires executive functions, compared with sham stimulation. To the best of our knowledge, this is the first clinical research reporting that tDCS over the FPA successfully improved the motor and non-motor functions in PD patients. These findings suggest that tDCS over the FPA might be a useful alternative for the treatment of PD patients.

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Fine Motor Function Skills in Patients with Parkinson Disease with and without Mild Cognitive Impairment

Cited by 30 publications

References 31 publications

Oral health of Parkinson’s disease patients, a case-control study

Oral health of Parkinson’s disease patients, a case-control study

Oral Health of Parkinson’s Disease Patients: A Case-Control Study

Effects of Transcranial Direct Current Stimulation (tDCS) Over the Frontal Polar Area on Motor and Executive Functions in Parkinson’s Disease; A Pilot Study

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