Fine‐needle aspirate of a large mass in the ventral peritoneal space of a dog

Abstract

| CASE PRESENTATIONAn 11-year-old, neutered male, Labradoodle was presented to the University of Florida's Small Animal Hospital for restaging of a meibomian gland carcinoma removed from his right inferior eyelid 3 years prior. On presentation, the dog had multiple masses throughout the body, including several subcutaneous lipomas and a cutaneous keratin-filled lesion between the ears, which were diagnosed by fine-needle aspiration and cytologic evaluation. A CBC and chemistry profile revealed a mild normocytic normochromic anemia (packed cell volume [PCV] 37%, reference interval [RI] 40-56; mean corpuscular volume [MCV] 69.2 fL, RI 64.0-74.0; mean corpuscular hemoglobin concentration (MCHC) 34.3, RI 33.0-38.0) and a moderately increased ALT activity (303 U/L, RI 18.0-64.0). A triple-phase helical computed tomography (CT) of the thorax, abdomen, and pelvis was performed for metastasis screening. A welldefined, heterogeneous, fat-and fluid-attenuating, bilobed mass was found within the left ventral peritoneal space, between the greater curvature of the stomach and the spleen, and ventral to the transverse colon. The mass measured approximately 12.0 × 6.5 × 6.5 cm (L × H × W) and was characterized by a soft tissue, contrast-enhancing capsule, a large, fluid-filled, non-contrast enhancing, irregularly margined central component, and multiple linear hyperattenuating striations within the fat-attenuating, non-contrast enhancing periphery (Figure 1). Multiple, hyperattenuating striations were seen within the peritoneal fat surrounding the mass. A fine-needle aspirate was submitted for cytologic evaluation (Figure 2).

Right axillary mass and decreased motor function in the right forelimb in a 5-year-old female bearded dragon

“…While necrotic lipomas have been described in dogs, cats, cows, and whales, they have not been described in bearded dragons. [1][2][3][4][5] Different types of lipoma tissue include simple lipomas, infiltrative lipomas, liposarcomas, and necrotic lipomas. 1 Simple lipomas are soft masses that are well demarcated and contain a thin capsule.…”

“…1 Simple lipomas tend to be subcutaneous and do not normally cause clinical signs; however, there have been reports of intra-abdominal and intrathoracic lipomas that caused space-occupying lesions. [1][2][3][4] The signs associated with these lesions are dependent on the adjacent organs. [1][2][3] Infiltrative lipomas are not well circumscribed and can invade surrounding tissue, including adjacent muscle, fascia, nerve, myocardium, joint capsule, and bone.…”

“…[1][2][3][4] The signs associated with these lesions are dependent on the adjacent organs. [1][2][3] Infiltrative lipomas are not well circumscribed and can invade surrounding tissue, including adjacent muscle, fascia, nerve, myocardium, joint capsule, and bone. 1 Liposarcomas are mesenchymal tumors that have a low metastatic potential but can invade regionally.…”

“…1 Necrotic lipomas have been known to mimic soft tissue masses of other origins in canine species and can be difficult to diagnose with CT and fine-needle aspirates alone. 1,2 The majority of lipoma lesions on CT appear as homogenous masses. 2 Liposarcomas usually appear as heterogenous with an often nodular nonadipose component.…”

“…1,2 The majority of lipoma lesions on CT appear as homogenous masses. 2 Liposarcomas usually appear as heterogenous with an often nodular nonadipose component. 2 The heterogenous appearance with areas of hyperattenuating components can represent necrosis, hemorrhage, fibrocollagenous septation, and residual muscular bands.…”