Fine needle aspiration at endoscopic ultrasound with a novel side-port needle: a pilot experience

Kaffes, Arthur J.; Corte, Crispin

doi:10.1177/1756283x11423295

Cited by 8 publications

(10 citation statements)

References 26 publications

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“…All data obtained is corrected for dead time, scatter, random counts and attenuation, automatically. The threshold value of metabolic index was set at 2.5 because this is the approximate physiologic background uptake of FDG in the body (range: 0.5 to 2.5), and is usually calculated using the liver as a reference point [ 9 ]. The standard uptake value, or SUV, is a semi-quantitative assessment of the radiotracer from a static PET image.…”

Section: Methodsmentioning

confidence: 99%

Endoscopic ultrasound – fine needle aspiration of 2-deoxy-2-[18F] fluoro-D-glucose avid lymph nodes seen on positron emission tomography- computed tomography –what looks like cancer may not always be so

et al. 2014

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Background Patients suffering from malignancies often undergo serial positron emission tomography - computed tomography (PET-CT) scans, using 2-deoxy-2-[ 18 F] fluoro-D-glucose (FDG) for diagnosis and follow up. This principle may also be applied to benign conditions as inflammatory cells take up increased amounts of FDG as well. The aim of our study was to retrospectively review the cytological diagnoses made at EUS-FNA of FDG-avid PET-CT lesions in patients with a history of cancer and to determine whether the cause of FDG-avidity was neoplastic or benign. Methods We used the endoscopy database to extract clinical information on all patients with malignancies who underwent EUS-FNA to obtain tissue from FDG-avid nodes seen on PET-CT at our institution from 2009 – 2012. All patients who were referred for EUS-FNA after their scans were included. Those who had contraindications to endoscopic procedures were excluded. Results The most common location of positive lymph nodes was the subcarinal region (46%). A definitive diagnosis was obtained in 87.8% cases, of which 51.2% had a diagnosis of malignancy confirmed on cytology, while 36.5% were benign. Out of these, 29% had granulomatous inflammation. In 12.2% of cases no definitive diagnosis was obtained. Conclusion Our results show that great caution should be exercised when evaluating FDG-avid PET-CT nodes in patients with known malignant disease, as a significant proportion of these lesions may be benign, particularly in geographic locations with a high background prevalence of granulomatous inflammation.

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Section: Methodsmentioning

confidence: 99%

Endoscopic ultrasound – fine needle aspiration of 2-deoxy-2-[18F] fluoro-D-glucose avid lymph nodes seen on positron emission tomography- computed tomography –what looks like cancer may not always be so

et al. 2014

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“…[11] A new 22-gauge needle from Olympus with prototype side-port has shown encouraging results for cytology, though further data are awaited. [12,13]…”

Section: Precautionsmentioning

confidence: 99%

Endoscopic ultrasound.guided fine-needle tissue acquisition – A review and update of literature

Tharian

George

Canipe

et al. 2015

Journal of Digestive Endoscopy

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Ever since the first endoscopic ultrasound-guided fine needle aspiration (FNA) was done in 1992, the procedure has evolved to become an indispensable tool for tissue acquisition in patients with gastrointestinal tumors and periluminal lesions. With the growing evidence of neoadjuvant therapy and research into intratumoral therapy, the need to obtain tissue diagnosis for tumors is quite apparent. This review provides an overall perspective to the endosonographer on various issues that are a key for best practices in FNA, in addition to being an update for practicing experienced endosonographers.

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“… 3 Recently, a new side-port needle has been developed by Olympus (Tokyo, Japan), and it is expected to allow better cellular acquisition. 4 …”

Section: Needles For Eus-guided Tissue Acquisitionmentioning

confidence: 99%

Fine-Needle Biopsy: Should This Be the First Choice in Endoscopic Ultrasound-Guided Tissue Acquisition?

Kim

2014

Clin Endosc

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Endoscopic ultrasound (EUS)-guided tissue acquisition is an indispensable technique for the diagnosis of many diseases of the gastrointestinal tract and adjacent structures. EUS-guided fine-needle aspiration (EUS-FNA) is known for its high accuracy and low complication rate. However, the outcome of EUS-FNA highly depends on several factors such as the location and characteristics of the lesion, endosonographer's experience, technique of sampling and sample preparation, type and size of the needle used, and presence of a cytopathologist for rapid on-site examination. EUS-guided fine-needle biopsy is useful to obtain core tissue samples with relatively fewer passes. Aspiration of core tissue with preserved architecture is beneficial for the diagnosis of certain diseases and the performance of ancillary testing such as tumor molecular profiling. Issues related to needle size, type, and their acquired samples for cytologic and histologic evaluation are discussed here.

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Fine needle aspiration at endoscopic ultrasound with a novel side-port needle: a pilot experience

Cited by 8 publications

References 26 publications

Endoscopic ultrasound – fine needle aspiration of 2-deoxy-2-[18F] fluoro-D-glucose avid lymph nodes seen on positron emission tomography- computed tomography –what looks like cancer may not always be so

Endoscopic ultrasound – fine needle aspiration of 2-deoxy-2-[18F] fluoro-D-glucose avid lymph nodes seen on positron emission tomography- computed tomography –what looks like cancer may not always be so

Endoscopic ultrasound.guided fine-needle tissue acquisition – A review and update of literature

Fine-Needle Biopsy: Should This Be the First Choice in Endoscopic Ultrasound-Guided Tissue Acquisition?

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