Fine needle aspiration biopsy in pediatric space-occupying lesions of liver: a retrospective study evaluating its role and diagnostic efficacy

Bakshi, Pooja; Srinivasan, Radhika; Rao, K. L. N.; Marwaha, Ram Kumar; Gupta, Nalini; Das, Ashim; Nijhawan, Raje; Rajwanshi, Arvind

doi:10.1016/j.jpedsurg.2006.06.027

Cited by 30 publications

(21 citation statements)

References 18 publications

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“…In one review of 44 pediatric patients who underwent fine needle aspiration, 26 (60%) were found to have neoplastic lesions, and malignancy accounted for 21 (87.5%) of these lesions (59). Other studies have similarly reported malignancy in about two-thirds of pediatric liver tumors that were biopsied (60, 61). …”

Section: Liver Tumorsmentioning

confidence: 78%

Liver Biopsy in Modern Clinical Practice

Ovchinsky

Moreira

Lefkowitch

et al. 2012

Advances in Anatomic Pathology

112

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Section: Liver Tumorsmentioning

confidence: 78%

Liver Biopsy in Modern Clinical Practice

Ovchinsky

Moreira

Lefkowitch

et al. 2012

Advances in Anatomic Pathology

112

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“…In children, there are only few studies done mainly in head and neck lesions, lymphadenopathy, renal, and liver space occupying lesions. [345678]…”

Section: Discussionmentioning

confidence: 99%

Fine needle aspiration cytology in pediatric age group with special reference to pediatric tumors: A retrospective study evaluating its diagnostic role and efficacy

Shetty

Suresh

et al. 2014

Ann Med Health Sci Res

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Background:Fine needle aspiration cytology (FNAC) is a well-established diagnostic technique in adult mass lesions but a comparatively new technique to pediatric lesions.Aim:The current study aims to evaluate the role of FNAC in pediatric age with special reference to pediatric tumors.Subjects and Methods:A retrospective study of FNAC in children ≤ 18 years of age presenting with mass lesions was studied for 5 years. Distribution of cases in different age groups, sex, and site of lesion was analyzed. Pediatric lesions were categorized into non-neoplastic, benign, and malignant conditions. Diagnostic efficacy was assessed by comparing subsequent histopathological examination wherever possible.Statistical Analysis:Epi info 07 (Centers for Disease Control and Prevention in Atlanta, Georgia (USA) 07) and values were presented as simple percentages.Results:FNAC was performed on 2903 cases in 5 years out of which 327 cases 11.3% (327/2903) were ≤ 18 years of age. Out of 327 cases, 180 cases 55% (180/327) were between 11 and 18 years. Male to female ratio was 1.15:1. The commonest site for FNAC was cervical lymph node swelling 48.3% (158/327). Reactive lymphadenitis was the commonest diagnosis among all mass lesions 38.8% (103/265), whereas Fibroadenoma 20.8% (10/49) was commonest diagnosis among benign lesions and among malignant lesions there were two cases 15.3% (2/13) each of Hodgkins and non-Hodgkins lymphoma and one case of chondrosarcoma. The positive predictive value of diagnosing malignant lesions on FNAC was 100%.Conclusions:The ease of FNAC along with its high diagnostic accuracy makes it a desirable method for diagnosing lesions in children.

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“…About one third of liver paediatric liver masses are benign. [7][8][9][10][11][12][13][14][15][16] A total of 10 patients with benign liver tumors were treated in our institute over a period of 10 years from January 2006 to December 2016. Seven of the 10 babies with benign liver tumors were haemangiomas, two were mesenchymal hamartomas, one with focal nodular hyperplasia.…”

Section: Discussionmentioning

confidence: 99%

Benign liver tumors in children-single centre experience

et al. 2017

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Background: To assess the incidence and management of benign liver tumors.Methods: Retrospective analysis of patients who were admitted with benign liver tumors in a Medical College Hospital in southern part of India during the period of 2006 to 2016 were analyzed.Results: We have treated a total of 10 cases of benign liver tumors during the period of 2006 to 2016. The mean age of presentation was 2.1 year. Seven of the ten cases were haemangiomas, two babies had mesenchymal hamartomas, one had focal nodular hyperplasia. Of the seven babies with haemangiomas, four had focal, two had diffuse involvement of liver, one baby had giant haemangioma. Three of the 4 babies with focal haemangiomas regressed during follow up, one baby lost follow up. One of the two babies with diffuse haemangioma developed high output cardiac failure but responded to digoxin, diuretics and steroids and now under follow up. The new born baby with giant haemangioma involving left lobe of liver also had high output heart failure which was refractory to medical therapy and required left lobectomy. Two babies had large mesenchymal hamartomas involving right lobe required surgical resection. One patient with focal nodular hyperplasia was managed conservatively. Mean follow up was 36 months. There were no deaths.Conclusions: Benign liver tumors are rare, most of them are haemangiomas. Only few of them require surgery. Large mesenchymal hamartomas can be promptly treated by resection with minimal mortality.

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Fine needle aspiration biopsy in pediatric space-occupying lesions of liver: a retrospective study evaluating its role and diagnostic efficacy

Cited by 30 publications

References 18 publications

Liver Biopsy in Modern Clinical Practice

Liver Biopsy in Modern Clinical Practice

Fine needle aspiration cytology in pediatric age group with special reference to pediatric tumors: A retrospective study evaluating its diagnostic role and efficacy

Benign liver tumors in children-single centre experience

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