Fine‐needle aspiration cytology and radiological imaging in parotid gland tumours: Our experience in 103 patients

Perkins, Clare; Toll, Edward; Reece, Philip

doi:10.1111/coa.13410

Cited by 5 publications

(5 citation statements)

References 10 publications

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“…12 PAs typically cover two thirds of the benign tumors of the salivary glands, 11 but only 47% of the benign epithelial tumors in the present study. In addition, 36% were Warthin tumors, which is significantly more than in other series (8%-15%), 15,17 but reflects figures presented by Perkins et al 18 Most malignant tumors in our study were SDCs (31%), a significantly differing finding from other studies where other tumor types predominate. 13,14,16,19 We encountered no adenoid cystic carcinomas (ACC), but noteworthy, the overall number of malignancies remained low.…”

Section: Discussioncontrasting

confidence: 58%

“…Efforts to minimize the occurrence of inadequate/inconclusive FNAC are required but additional imaging might also prove of value in these cases. Perkins et al stated that combining preoperative imaging significantly improves the results of FNAC 18 . We feel that when a lesion is regarded as benign and if omission of surgery is planned, further imaging (MRI) and/or follow‐up seem advisable and informing the patient to contact the department in case of new symptoms.…”

Section: Discussionmentioning

confidence: 98%

“…This raises a question whether surgery was even beneficial for them. 18 We feel that when a lesion is regarded as benign and if omission of surgery is planned, further imaging (MRI) and/or follow-up seem advisable and informing the patient to contact the department in case of new symptoms.…”

Section: Discussionmentioning

confidence: 99%

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Preoperative evaluation and treatment consideration of parotid gland tumors

Aro

Korpi

Tarkkanen

et al. 2020

Laryngoscope Investig Oto

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Background The nature of parotid tumors often remains unknown preoperatively and final histopathology may reveal unexpected malignancy. Still, the use of fine‐needle aspiration cytology (FNAC) and imaging varies in the management of these tumors. Methods We evaluated the preoperative examinations and management of all 195 parotid gland tumors diagnosed within our catchment area of 1.6 million people during 2015. Results Altogether 171 (88%) tumors were classified as true salivary gland neoplasms. FNAC showed no false malignant findings, but it was false benign in 5 (2.6%) cases. Preoperative MRI was utilized in 48 patients (25%). Twenty (10%) malignancies included 16 salivary gland carcinomas. Pleomorphic adenomas accounted for 52% of all adenomas. For 24 (40%) Warthin tumors, surgery was omitted. Conclusion The proportion of malignancies was lower than generally presented. Our proposed guidelines include ultrasound‐guided FNAC with certain limitations. MRI is warranted in selected cases, but seems unnecessary routinely.

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Section: Discussioncontrasting

confidence: 58%

Section: Discussionmentioning

confidence: 98%

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Preoperative evaluation and treatment consideration of parotid gland tumors

Aro

Korpi

Tarkkanen

et al. 2020

Laryngoscope Investig Oto

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“…According to the results of the reviewed studies, FNAB has a Se between 55.6 and 94.1%, a Sp between 75% and 98%, www.bjbms.org a PPV between 60% and 90%, a NPV between 86% and 98%, a non-diagnostic rate between 3% and 28.9%, and even 68% according to one author, and an overall accuracy between 60.8% and 98% [71]. The accuracy of FNAB in the diagnosis of tumor histological type is low (18-35%) [6,7,69,[71][72][73][74][75]. The FNAB accuracy can be increased by examining the material immediately after sampling, by an experienced operator and interpretation of the result by a specialized pathologist and by using the US guidance; US guidance can avoid harvesting cytological material from tumor necrotic areas and confirms the presence of the needle tip in the center of the parotid tumor [72].…”

Section: Fnab and Core Needle Biopsy (Cnb)mentioning

confidence: 99%

Cross-sectional imaging and cytologic investigations in the preoperative diagnosis of parotid gland tumors – an updated literature review

Stoia

Băciuț

Lenghel

et al. 2020

Bosn J of Basic Med Sci

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An accurate preoperative diagnosis of parotid tumors is essential for selection and planning of the surgical treatment. Various modern cross-sectional imaging and cytologic investigations can support differential diagnosis of parotid tumors. The aim of this study was to achieve a comprehensive and updated review of modern imaging and cytologic investigations used in parotid tumor diagnosis, based on the latest literature data. This literature review could serve as a guide for clinicians in selecting different types of investigations for preoperative differential diagnosis of parotid tumors. Magnetic resonance imaging (MRI) with its dynamic and advanced sequences is the first-line imaging investigation used in differentiating parotid tumors. Computed tomography (CT) and positron emission tomography (PET)-CT provide limited indications in differentiating parotid tumors. Fine needle aspiration biopsy and core needle biopsy can contribute with satisfactory results to cytological diagnosis of parotid tumors. Dynamic MRI with its dynamic contrast-enhanced and diffusion-weighted sequences provides the best accuracy for preoperative differential diagnosis of parotid tumors. CT allows the best evaluation of bone invasion, being useful when MRI cannot be performed, and PET-CT has value in the follow-up of cancer patients. The dual cytological and imaging approach is the safest method for an accurate differential diagnosis of parotid tumors.

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“…The prognosis and management of these tumours are significantly different. The sensitivity of pre-operative FNAC in differentiating benign and malignant salivary gland tumours is variable in different studies (52.0-98.5%) [2][3][4][5]. In addition, FNAC is especially difficult for tumours involving the deep lobe of the parotid gland.…”

Section: Introductionmentioning

confidence: 99%

Differentiation of various salivary gland tumours using diffusion-weighted MRI and dynamic contrast-enhanced MRI

Kushwaha¹,

Kumar²,

Garg³

et al. 2023

Pol J Radiol

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Purpose To determine the role of functional magnetic resonance imaging techniques (diffusion-weighted magnetic resonance imaging [DW-MRI] and dynamic contrast-enhanced magnetic resonance imaging [DCE-MRI]) in the differentiation of various salivary gland tumours. Material and methods In this prospective study, we evaluated 32 patients with salivary gland tumours using functional MRI. Diffusion parameters (mean apparent diffusion coefficient [ADC], normalized ADC and homogeneity index [HI]),semiquantitative DCE parameters (time signal intensity curves [TICs]) and quantitative DCE parameters (K ep , K trans and V e ) were analysed. Diagnostic efficiencies of all these parameters were determined to differentiate benign and malignant tumours as well as to characterize 3 major subgroups of salivary gland tumours, namely pleomorphic adenoma, Warthin tumour, and malignant tumours. Results Mean ADC, normalized ADC and HI were insignificant in differentiating benign and malignant tumours but were significant in differentiating pleomorphic adenomas, Warthin tumours, and malignant tumours. Mean ADC was the best parameter in predicting both pleomorphic adenomas and Warthin tumours (AUC: 0.95 and 0.89, respectively). Amongst DCE parameters, only TIC pattern could differentiate between benign and malignant tumours, with an accuracy of 93.75% (AUC: 0.94). The quantitative perfusion parameters aided greatly in characterizing pleomorphic adenomas, Warthin tumours and malignant tumours. For predicting pleomorphic adenomas, the accuracy of K ep and K trans was 96.77% (AUC: 0.98) and 93.55% (AUC: 0.95), respectively and for predicting Warthin tumours, the accuracy of both K ep and K trans was 96.77% (AUC: 0.97). Conclusions DCE parameters (particularly TIC, K ep and K trans ) had higher accuracy in characterizing various tumour subgroups (pleomorphic adenomas, Warthin tumours, and malignant tumours) than DWI parameters. Hence, dynamic contrast-enhanced imaging adds immense value with only a minimum time penalty to the examination.

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Fine‐needle aspiration cytology and radiological imaging in parotid gland tumours: Our experience in 103 patients

Cited by 5 publications

References 10 publications

Preoperative evaluation and treatment consideration of parotid gland tumors

Preoperative evaluation and treatment consideration of parotid gland tumors

Cross-sectional imaging and cytologic investigations in the preoperative diagnosis of parotid gland tumors – an updated literature review

Differentiation of various salivary gland tumours using diffusion-weighted MRI and dynamic contrast-enhanced MRI

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