Fine needle aspiration cytology-based accurate and rapid diagnosis of breast tuberculosis masquerading as a case of abscess

Yethindra, Vityala; Zhumabekova, Altynai; Dzhumakova, Cholpon; Tagaev, Tugolbai; Namazbekova, Asel; Djanaliev, Bolotbek

doi:10.22541/au.161320457.73605835/v1

Cited by 1 publication

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“…The results revealed that administering a prophylactic and therapeutic regimen of liposomal doxorubicin in conjunction with tamoxifen significantly suppressed tumor growth and was relatively safe. [13] These results corroborate the hypothesis that the antitumor activity of MCP is entirely dependent on the molecular weight of this polymer. When pectin, metformin, and chemotherapy were combined, a limited antitumor effect on SARC-45 was observed when paired with doxorubicin, with a negative TGI on the 24 th day of the study.…”

Section: Discussionsupporting

confidence: 81%

Untitled

2024

AJP

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Introduction:Radiation therapy, a commonly used treatment for various types of cancer, has toxic effects on the body. To counter this, researchers have developed medications that minimize the harmful effects of ionizing radiation on normal cells and tissues, while enhancing the effect of radiation on cancerous cells. These drugs are known to be radiosensitizers or radiomimetic agents. This study investigated the effectiveness of modified citrus pectin (MCP) and metformin combined with radiation therapy and chemotherapy. Materials and Methods: This study used 380 Wistar rats with transplantable strains and two types of cancer cells. The experimental therapy included administration of sugar beet pectin, MCP, and metformin. Effectiveness was determined by commonly accepted indicators, such as the percentage of tumor growth inhibition and increased lifespan. Results: MCP and sugar beet pectin had radiomodifying properties and enhanced the sensitivity of cancer cells to radiation therapy. The combination of MCP and metformin had a positive effect on cancer treatment, with complete regression or disappearance of the tumor by the 15 th day, and the lifespan of the animals increased by approximately 430%. Conclusion:The use of pectin and MCP as radiomodifiers could potentially improve the effectiveness and reduce the toxicity of anti-tumor therapy. This study suggests that the combination of MCP and metformin with radiation therapy and chemotherapy may be a promising approach for cancer treatment.

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Section: Discussionsupporting

confidence: 81%

Untitled

2024

AJP

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Fine needle aspiration cytology-based accurate and rapid diagnosis of breast tuberculosis masquerading as a case of abscess

Cited by 1 publication

References 14 publications

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