Fine needle aspiration cytology in ovarian lesions: an institutional experience of 584 cases

Abstract

FNAC has a high specificity for diagnosis of ovarian/adnexal lesions but greater experience is required for the accurate subtyping of neoplasms and sensitivity is limited by inconclusive/inadequate results.

http://www.omicsonline.org/open-access/accuracy-of-combined-tru-cut-and-fnac-in-preoperative-sampling-of-ovarian-tumors-2161-0681.1000168.php?aid=26242

“…On the other hand, the diagnostic accuracy for FNAC in our study was within the range reported by most of the studies like that of Bandyopadhyay et al [6], Sood et al [14], Freedman et al [4], Hemalatha et al [17], and Gupta et al [16], that were (97.06%, 98%, 96.2%, 96.3%, 92% respectively). But it was slightly higher than that reported by Khan et al [19] that was (89.9%) and Stewart et al [23] that was (86.5%), and prominently higher than that reported by Mehdi et al [13] that was (80.9%).…”

“…It may be of importance to mention that germ cell as well as sex cord stromal tumors namely granulosa cell tumor are more likely to be typed on FNAC than surface epithelial ones. A view supported by Mathur [24] and Gupta et al [16]. In our study we didn't have cases diagnosed as sex cord stromal tumor.…”

“…Considering the role of FNAC alone, it was addressed in more studies some of which were specific for ovarian masses including Bandyopadhyay et al [6], Mehdi et al [13], Sood et al [14], Goel et al [15], and Gupta et al [16]. Others like Hemalatha et al [17] studied the role of FNAC in abdomino-pelvic masses in general including ovarian masses as part of their studied population.…”

Accuracy of Fine Needle Aspiration of Pelvic Masses, A Cyto-histological Correlation

“…Recently Gupta et al, in a retrospective study of ultrasound-guided (US) FNAC of 584 ovarian lesions evaluated that FNAC sensitivity for a diagnosis of malignancy was 85.7%, specificity 98.0%, positive predictive value 97.7%, negative predictive value 87.7% and accuracy 92.0%. They concluded that FNAC has a high specificity for diagnosis of ovarian/adnexal lesions but greater experience is required for the accurate subtyping of neoplasms and sensitivity is limited by inconclusive/inadequate results [19].…”

USG guided FNAC of ovarian mass lesions: A cyto-histopathological correlation, with emphasis on its role in pre-operative management guidelinesö

“…Among the available imaging modalities, ultrasonography (USG) is economical, rapid and widely available, not only providing substantial information regarding the nature of the mass but also guiding the fine-needle aspiration (FNA) with adequate precision (6). Previous studies have attempted to estimate the efficacy of image-guided FNAC in the accurate preoperative diagnosis of ovarian lesions (1,(5)(6)(7)(8). The main aim of this study was to assess the sensitivity, specificity and diagnostic accuracy of USG-guided FNAC in the distinction of neoplastic and non-neoplastic ovarian masses, considering histopathology as the gold standard.…”