Fine needle aspiration cytology in the head and neck region

McLean, N.R.; Harrop‐Griffiths, Katherine; Shaw, H. J.; Trott, P. A.

doi:10.1016/0007-1226(89)90012-x

Cited by 12 publications

(9 citation statements)

References 9 publications

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“…FNAC materials also permit the supplementary studies such as immunohistochemistry, electron microscopy, morphometric studies for diagnosis of specific typing of lesions 6,10,11. As information on the biological behaviour of a lesion in the preoperative period is very important, FNAC is a good starting point for the diagnosis and may clarify the next step as a minimally invasive procedure 12. In the present research, some lesions that resemble an odontogenic cyst radiographically were diagnosed as central giant cell granuloma, myxoma or cystic ameloblastoma by FNAC (Figures 1 and 2).…”

Section: Discussionmentioning

confidence: 99%

“…However, it is reported that, the diagnosis of aspirates from cystic lesions may be less specific than the FNAC diagnosis of solid lesions due to the paucity of specific lesional cells in the former 5,12. A diagnosis of ‘benign cystic lesion’ is justified in many instances.…”

Section: Discussionmentioning

confidence: 99%

“…Ramzy et al13 reported that cysts of the jawbones may pose a problem in the differential diagnosis and exact location, history and radiological appearances must be considered before definitive cytological diagnosis is made. Lindberg and Akerman12 stated that the cystic character of the aspirate increases the number of false negatives in the salivary gland lesions. Dejmek and Lindholm5 suggested that non-diagnostic samples in their series were fewer among cystic lesions in contrast to the often-expressed diagnostic difficulties associated with them.…”

Section: Discussionmentioning

confidence: 99%

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The Value of Aspiration Cytology in Cystic Lesions of the Maxillofacial Region

2010

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Objectives:The majority of the pathologic structures which are seen in the oral and maxillofacial region are either cystic or tend to show cystic changes. They may have not specific clinical and radiographic findings. Therefore, it is difficult to differentiate these lesions preoperatively. For this purpose, in this research, the value of fine-needle aspiration cytology (FNAC) in preoperative diagnosis was investigated by comparing with the postoperative histopathologic diagnosis.Methods:One hundred aspirates from cystic lesions in the oral and maxillofacial region were included in this study. All of the samples except one were examined histopathologically and the results were compared.Results:The results of the FNAC specimens obtained from 100 lesions were compared with histopathologic diagnosis of these lesions. According to these results, 12 insufficient (12%), 7 positive (7%), 81 negative (81%) specimens were obtained. Among these 88 lesions, 69 of them were diagnosed specifically by cytological examination (78.4%). 62 of the 69 specific diagnoses achieved by cytological examination were confirmed histopathologically (89.85%). The histological types of the seven lesions were missed by cytological examination. There were not any complications related with the fine-needle aspiration procedure in the research.Conclusions:According to these results, the value of fine-needle aspiration biopsy in cystic lesions of the maxillofacial region is found as successful as in the solid lesions.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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The Value of Aspiration Cytology in Cystic Lesions of the Maxillofacial Region

2010

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“…When stasis occurs, an amorphous material, chylomicra or thrombi of platelets, and necrotic debris clog the vascular lumen [56] . Animal studies have shown that the presence of infection and sepsis induces a significant increase in thrombosis and distant pyogenic abscesses [56][57][58] . Autopsy cases have shown pulmonary microthrombi and partially dissolved fibrin in vessels of burn patients contributing to sludging of cells in vessels [59] .…”

Section: Thrombosis and Thromboembolismmentioning

confidence: 99%

Antithrombin in the treatment of burn trauma

Kowal-Vern

Orkin

2016

WJCCM

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Antithrombin (AT) is a natural anticoagulant with antiinflammatory properties that has demonstrated value in sepsis, disseminated intravascular coagulation and in burn and inhalation injury. With high doses, AT may decrease blood loss during eschar excision, reducing blood transfusion requirements. There are no human randomized, placebo-controlled studies, which have tested the true benefit of this agent in these conditions. Two main forms of AT are either plasma-derived AT (phAT) and recombinant AT (rhAT). Major ovine studies in burn and smoke inhalation injury have utilized rhAT. There have been no studies which have either translated the basic rhAT research in burn trauma, or determined the tolerance and pharmacokinetics of rhAT concentrate infusions in burn patients. Advantages of rhAT infusions are no risk of blood borne diseases and lower cost. However, the majority of human burn patient studies have been conducted utilizing phAT. Recent Japanese clinical trials have started using phAT in abdominal sepsis successfully. This review examines the properties of both phAT and rhAT, and analyzes studies in which they have been utilized. We believe that it is time to embark on a randomized placebo-controlled multi-center trial to establish the role of AT in both civilian and military patients with burn trauma.

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“…The diagnosis and subsequent treatment of patients with head and neck neoplasia is usually predicated on tissue sampling. Fine needle aspiration biopsy is now commonplace and is highly reliable 1‐4 . Less common is the use of core biopsy for histologic study because of the concern of seeding tumor cells along the tract.…”

Section: Introductionmentioning

confidence: 99%

Interactive Magnetic Resonance Imaging‐Guided Biopsy in the Head and Neck: Initial Patient Experience

Fried¹,

Hsu²,

Jólesz³

1998

The Laryngoscope

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Because of its excellent soft tissue resolution, magnetic resonance imaging (MRI) can optimize image guidance for interventional and surgical procedures. Notably, needle biopsy of head and neck lesions has been used for years, deeper lesions often requiring some form of image guidance. The closed space of diagnostic MRI scanners proves cumbersome for intervention. The authors report on the first head and neck image-guided biopsies performed in a new, investigational "open configuration" intraoperative MRI scanner. Vertical space between the scanner's upright coils gives access to the patient while imaging; image acquisition is as fast as 2 sec/image. Biopsies were performed on seven patients (parotid, parapharyngeal space, second cervical vertebra); five specimens were diagnostic. Both general anesthesia and intravenous sedation were used. The procedures were without complications. Imaging provided definition of anatomy to direct needle placement. Access to the patient allowed for both percutaneous and transoral approaches. The environment of the open magnet is well suited for biopsy of the head and neck, and near real-time intraoperative MRI has promise for guiding more complex head and neck procedures. Further study should optimize the quality of the images and the interactibility of localization and targeting and fully utilize MRI's three-dimensional imaging capabilities.

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Fine needle aspiration cytology in the head and neck region

Cited by 12 publications

References 9 publications

The Value of Aspiration Cytology in Cystic Lesions of the Maxillofacial Region

The Value of Aspiration Cytology in Cystic Lesions of the Maxillofacial Region

Antithrombin in the treatment of burn trauma

Interactive Magnetic Resonance Imaging‐Guided Biopsy in the Head and Neck: Initial Patient Experience

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