Fine-Needle Aspiration Cytology of Hepatic Angiomyolipoma: Case Report with Histological, Immunohistochemical and Electron Microscopic Findings

Nazer, Mona Al; Ali, Mohammed Ashraf

doi:10.5144/0256-4947.2001.330

Cited by 2 publications

(2 citation statements)

References 23 publications

(23 reference statements)

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“…Fine needle aspiration cytologic findings of renal AMLs (reviewed in Ref. 37) and hepatic AMLs 2, 16, 22–31 are well described (Table I). However, most reported cases are examples of classic triphasic AMLs.…”

Section: Discussionmentioning

confidence: 98%

“…Our case had many of the cytologic features previously reported in epithelioid hepatic AMLs. 2, 16, 22–31 These included the presence of naked nuclei, epithelioid cells in clusters and as single cells, low nucleocytoplasmic ratio, fibrillary, frothy or finely granular cytoplasm, and indistinct cell borders, bland nuclei with indistinct nucleoli, focal intranuclear pseudoinclusions and mild pleomorphism, as well as the presence of extramedullary hematopoiesis. In addition, our case also showed some unusual cytologic features, such as the presence of mast cells, intracytoplasmic erythropoietic elements and hyaline inclusions.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Transcatheter coil occlusion of perimembranous ventricular septal defects

Nogi¹,

Haneda²,

Tomita³

2008

Cathet Cardio Intervent

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Transcatheter coil occlusion of perimembranous ventricular septal defects

Nogi¹,

Haneda²,

Tomita³

2008

Cathet Cardio Intervent

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show abstract

Hepatic epithelioid angiomyolipoma with trabecular growth pattern: A mimic of hepatocellular carcinoma on fine needle aspiration cytology

Xie

Jessurun

Pambuccian

2011

Diagnostic Cytopathology

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Epithelioid angiomyolipomas (AMLs) of the liver are rare tumors with imaging and cytologic features overlapping with those of hepatocellular carcinomas. We report the fine needle aspiration and core biopsy findings of an epithelioid AML in the right hepatic lobe of a 32-year-old female with tuberous sclerosis. She had undergone renal transplantation 8 years previously after bilateral nephrectomy for renal AMLs and a 3-cm chromophobe renal cell carcinoma. Hepatocellular carcinoma was suspected during the initial cytologic and histologic examination based on the presence of numerous large polygonal cells with ample finely vacuolated or granular cytoplasm, low nucleocytoplasmic ratio, and mild nuclear pleomorphism in the smears, as well as a distinctive trabecular histologic pattern in the core biopsies. Immunoperoxidase stains showed that the neoplastic cells were negative for cytokeratins and positive for HMB45, Melan-A, and smooth muscle actin, establishing the diagnosis of epithelioid AML. To determine the distinguishing cytomorphologic features between epithelioid AML and HCC, we have compared the cytologic features of 15 cases of hepatic AML reported in the literature, including the present case, to the FNA cytologic findings of 38 consecutive cases of HCC diagnosed at out institution.

show abstract

Fine-Needle Aspiration Cytology of Hepatic Angiomyolipoma: Case Report with Histological, Immunohistochemical and Electron Microscopic Findings

Cited by 2 publications

References 23 publications

Transcatheter coil occlusion of perimembranous ventricular septal defects

Transcatheter coil occlusion of perimembranous ventricular septal defects

Hepatic epithelioid angiomyolipoma with trabecular growth pattern: A mimic of hepatocellular carcinoma on fine needle aspiration cytology

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