Fine Needle Aspiration Cytology of Abdominal Organs – Ten Year Single Center Experience

Abstract

SUMMARY -The aim of the study was to assess the role of fine needle aspiration cytology (FNAC) in the diagnosis of focal changes in solid abdominal organs. A total of 1084 aspirates from intra-abdominal organs including liver, spleen, pancreas and kidneys obtained by ultrasound (US) guidance during a 10-year period were included in the study. The smears were classified as benign, malignant or suspected of malignancy, and unsatisfactory for interpretation. The liver accounted for more than half of the US-guided FNA procedures, followed by the pancreas with 38%. Out of 1084 aspirations, 192 (17.7%) were inadequate for cytologic analysis. Over half of aspirated lesions in the pancreas were primary cancers, while one-third of pancreatic lesions were benign. In the majority of kidney lesions (83%), cytology found benign changes, mostly cysts. Spleen FNA was least likely; in most cases (59%) it showed lymphoid tissue hyperplasia; in four cases cytologic diagnosis was lymphoma and three lesions were suspected lymphoma. During the study, no major complications were observed on any US-guided FNAC procedure. In conclusion, intra-abdominal FNA is a reliable, sensitive and specific method with a high diagnostic accuracy for the diagnosis of malignant lesions. It can be utilized as a preoperative procedure for the management of all intra-abdominal lesions.

Correlation of cytopathology with flow cytometry and histopathology for the diagnosis of hematologic malignancies in young adults presenting with cervical lymphadenopathy

“…Causes of cervical lymphadenopathy vary based on age. Overall, benign reactive lymph node aspirates comprise a large portion of the diagnoses in patients from pediatric and adult populations . In concordance to the previous studies, the majority of cases from our series were samplings of benign reactive lymph nodes, totaling 36 of the 48 patients (75%).…”

“…Overall, benign reactive lymph node aspirates comprise a large portion of the diagnoses in patients from pediatric and adult populations. [10][11][12][13][14] In concordance to the previous studies, the majority of cases from our series were samplings of benign reactive lymph nodes, totaling 36 of the 48 patients (75%). Nineteen patients had only cytologic assessment without further workup due to minimal clinical concern and did not develop subsequent hematologic malignancies.…”

Fine needle Aspiration Cytology of various Head and Neck Swellings

“…FNAC is a simple, reliable and inexpensive diagnostic tool in evaluation of HN swellings. [7][8][9] It causes minimal trauma to the patient and carries virtually no risk of complications. [10][11][12][13][14] It is an outdoor procedure which is safe and well accepted.…”

Measurable and Unmeasurable Features of Ultrasound Lymph Node Images in Detection of Malignant Infiltration

“…It has been previously shown that of all peripheral LNs, cervical LNs were most commonly identifi ed by both physicians and patients. In addition, over fi fty percent of lymphadenopathies have been located in the head and neck region [16][17][18] .…”