Fine-needle aspiration cytology of ovarian steroid cell tumor: A rare case report

Abstract

Steroid cell tumors (SCTs) of the ovary are a rare subgroup of sex cord tumors that account for less than 0.1% of all ovarian tumors. These tumors can produce steroids, especially testosterone, which produces symptoms such as hirsutism, amenorrhea/oligomenorrhea, and male patterned voice. For evaluation of the androgen excess, testosterone and dehydroepiandrosterone sulfate (DHEA-S) are the first laboratory tests to be measured. Abdominal ultrasound and magnetic resonance imaging (MRI) are useful radiologic imaging techniques. Although SCTs are generally benign, the risk of malignant transformation is always present. Surgical excision of tumor is the most important and hallmark treatment. The present case signifies the early preoperative diagnosis of a virilizing SCT, based on cytological features and its careful correlation with clinicopathological and radiological findings.

Giant ovarian serous cyst and postmenopausal adnexal torsion: An unusual case report and literature review

“…This may involve collaboration between gynecologic oncologists, urologists, and other specialists to ensure the best possible outcomes for patients. By working together, these experts can develop a comprehensive plan for managing potential complications and ensuring the safety and success of the procedure [ 13 ].…”

Cytological Findings of Ascitic Fluid with a Malignant Ovarian Steroid Cell Tumor: A Case Report and Literature Review

“…These cytological findings are consistent with the pathologic findings of typical SCTs. Agrawal et al [7] were the first to report an early preoperative diagnosis of a SCT, made by correlating cytology with clinicopathologic and radiologic findings.…”

“…Agrawal et al [7] described a patient who underwent ultrasound-guided FNAC that revealed large, polygonal-to-round cells arranged in sheets and attached to vascular stromal tissue fragments; the cells had small, central, round nuclei with conspicuous nucleoli and abundant, granular to pale, multivacuolated (foamy) cytoplasm. These cytological findings are consistent with the pathologic findings of typical SCTs.…”