Fine needle cytology features of an atypical presentation of infectious mononucleosis

Gerber-Mora, Roberto; Lillo, Verónica Peña y; Moreno-Silva, Ricardo; González‐Arriagada, Wilfredo Alejandro

doi:10.4103/jomfp.jomfp_80_17

Cited by 2 publications

(1 citation statement)

References 16 publications

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“…If the immunity is compromised, virus may replicate in an uncontrolled manner; causing lymphoma. Moreover, if latent infection develops then memory B cells may persist for life [15] .…”

Section: Discussionmentioning

confidence: 99%

Emperipolesis, Apoptosis and Hemophagocytosis during Acute Epstein-Barr Virus (EBV) infection: A Case Report

Mehrotra

2023

jmscr

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An eight-year-old patient had intermittent high grade fever and pharyngitis since one week. Later, he developed left-sided cervical lymphadenitis. Subsequently, he also developed palatal petechiae. Absolute lymphocyte count (ALC) was raised (ALC 20,262 cells/mm³). Hepatosplenomegaly was also detected. Clinically, the current case was diagnosed as a case of infectious mononucleosis. Possibility of infection by Epstein-Barr virus was considered. FNAC was done. Blood-mixed aspirate showed monocytoid cells with mild pleomorphic nuclei, and clumped chromatin. Inconspicuous nucleoli and abundant eosinophilic cytoplasm were seen. Foci of apoptosis were also seen. Frequent mitoses were seen. Findings were suggestive of acute reactive lymphocytic hyperplasia with hemophagocytosis and apoptosis. EBV DNA was detected by RT PCR with linear reporting range of 3.3×104 IU/ml. Herewith, we describe a case of infectious mononucleosis with emperipolesis and hemophagocytosis. Keywords: Epstein-Barr virus associated hemophagocytosis syndrome (EBVAHS).

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“…If the immunity is compromised, virus may replicate in an uncontrolled manner; causing lymphoma. Moreover, if latent infection develops then memory B cells may persist for life [15] .…”

Section: Discussionmentioning

confidence: 99%