Fine Structure of Motor Endplate in Red, White and Intermediate Fibers of Mammalian Fast Muscle

Ogata, Takuro; Murata, Fumio

doi:10.1620/tjem.98.107

Cited by 18 publications

(7 citation statements)

References 1 publication

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“…The qualitative ultrastructural features of the three fiber types have been utilized to classify fibers in investigations of the NMJ of myofiber types (Ogata, 1964;Ogata et al, 1967;Ogata and Murata, 1969a;Murata and Ogata, 1969;Padykula and Gauthier, 1970;Duchen, 1971). Stereological studies of the NMJ of fiber types and quantitative comparison of their morphology are nonexistent.…”

Section: Discussionmentioning

confidence: 99%

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Direct correlation of histochemical profile to the ultrastructure of single myofibers and their neuromuscular junctions from a mixed muscle

1982

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It has been demonstrated that there are significant differences in the ultrastructural morphology of the three mammalian myofiber types and their neuromuscular junctions (NMJ). The description of these ultrastructural differences was based primarily on samples taken from muscles that were composed of predominantly one fiber type. The objectives of this study were 1) to determine if previously described ultrastructural characteristics could distinguish between the three fiber types and the NMJ in a mixed muscle containing similar percentages of each fiber type and 2) to determine if there were significant differences in the morphology of like fiber types when compared between two histochemical regions in a muscle with a compartmentalized fiber-type distribution. The muscle used in this study was the flexor carpi radialis (FCR) of the cat. The objectives were achieved by a direct correlation of ultrastructure to histochemical profile on the same isolated myofibers. This study revealed a wide range of morpohological variation among fiber types in the FCR. Although many fibers from the FCR could be classified by using accepted ultrastructural criteria, most could not. Compartmental differences were present in several of the ultrastructural parameters measured. The slow-twitch oxidative (SO) and fast-twitch oxidative-glycolytic (FOG) fibers in the oxidative compartment had a significantly larger myofiber core volume when compared to the fast-twitch glycolytic (FG) fibers from both compartments. Also, the FG fibers in the glycolytic region had a significantly larger membrane volume (terminal cisternae, T tubules, and sarcoplasmic reticulum) when compared to the FOG fibers in the oxidative compartment and the SO fibers in both regions.This study has demonstrated that considerable variation exists in the most commonly accepted ultrastructural features used for distinguishing the three myofiber types when sampled from a mixed muscle that is not dominated by one fiber type. These results suggest the possibility of a greater functional range in the same type of histochemically identified motor units from mixed muscle than in those from muscles containing predominantly one fiber type.Classifications of mammalian myofiber types have used a variety of criteria to distinguish among fiber types (e.g., histochemical profile, physiological properties, and morphology; see reviews by Close, 1972;

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Section: Discussionmentioning

confidence: 99%

“…Investigations of the ultrastructure of the neuromuscular junction (NMJ) described differences in this structure among the three mammalian fiber types (Ogata, 1964;Ogata et al, 1967;Ogata and Murata, 1969a;Murata and Ogata, 1969;Padykula and Gauthier, 1970;Duchen, 1971). The NMJ of the FOG myofiber has small elliptical axon terminals.…”

mentioning

confidence: 99%

Direct correlation of histochemical profile to the ultrastructure of single myofibers and their neuromuscular junctions from a mixed muscle

1982

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“…The properties of muscle fibers are also associated with the different types of muscle in terms of size and innervation (e.g., cat, Nystrom, 1968; rabbit, Dias and Spimpson, 1974; rat, Lomo and Wwhaug, 1985). The size of endplates suggests a relationship to the size of muscle fibers (mouse, Ogata, 1965;Harris and Ribchester, 1979;Padykular and Gauthier, 1970). Large endings make large contributions to movements (Rosenheimer, 1985).…”

Section: Light Microscopic and Scanning Electron Microscopic Observatmentioning

confidence: 99%

Morphology of the Nerve Terminals of Laryngeal Muscles in the Japanese Monkey (Macaca fuscata)

Sato

Shimada

Ezure

et al. 1995

Okajimas Folia Anatomica Japonica

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Summary: Laryngeal muscles, namely, the cricothyroid (CT), lateral crico-arytenoid (LCA), thyrio-arytenoid (TA), posterior crio-arytenoid (PCA), interarytenoid (IA) muscles, of Japanese monkeys (body weight, 4.4-8.3 kg; 3-10 years old, male) were examined histologically and by light and scanning electron microscopy. The diameter of muscle fibres with nerve terminals in the CT of the Japanese monkey was larger than that of other laryngeal muscles. However, the areas of nerve terminals varied among laryngeal muscles. The mean diameters of nerve terminals of the CT and PCA were large and basically resembled those of other laryngeal muscles. They contribute mainly to maintenance of phonation which the adductor muscles contribute mainly to postural adjustments of the cartilage. The differences in features of nerve terminals of each muscle suggest the CT and PCA may contribute mainly to the frequency or pitch of voice and intensity of the voice during vocalization and to respiration.The laryngeal muscles of mammals have various enzymatic profiles (e.g

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“…However, there is conflicting evidence whether the morphology of the endplate is related to fibre type (Burke, 1981). Other studies have found that slow fibres have smaller endplates (Ogata, 1965;Harris and Ribchester, 1979;Padykula and Gauthier, 1970). Slow-twitch muscles are the most frequently activated, therefore a large endplate may be of advantage if it contained a larger supply of transmitter.…”

Section: The Endplatementioning

confidence: 99%

Functional and structural changes of rat plantaris motoneurons following compensatory hypertrophy of the muscle

Finkelstein¹,

Lang²,

Luff³

1991

Anat. Rec.

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The conduction velocity and histological structure of motoneurons innervating normal and hypertrophied rat plantaris muscles were investigated. Hypertrophy was produced by ablation of synergist muscles. Single motor units were obtained by ventral root dissection and conduction velocities measured. The structure of neurons was investigated following retrograde labeling with horseradish peroxidase. A combined silver, gold and cholinesterase staining method was developed to study the motor endplate. In addition, the peripheral nerve was fixed, embedded in Araldite, and sectioned for determination of axonal size and myelin thickness. Conduction velocity of motor axons decreased following hypertrophy of the skeletal muscle (control CV = 75.8 +/- 8.9 m s-1, n = 94, hypertrophy CV = 69.0 +/- 12.3 m s-1, n = 84). However, no alteration in the size of motor axons or myelin thickness could account for this alteration in conduction velocity. Mean motoneuronal soma size decreased following muscle hypertrophy (soma diameter: control 36.1 +/- 4.6 microns, n = 283, hypertrophy 32.9 +/- 4.5 microns, n = 294). The complexity of the motor endplate increased following hypertrophy with an increased occurrence of nodal sprouts. In addition, the area of cholinesterase staining increased following hypertrophy (control 588.1 +/- 297.2 microns 2, n = 269, hypertrophy 857.7 +/- 357.0 microns 2, n = 269). This study found that both the morphological and physiological parameters of motoneurons innervating a hypertrophied muscle were shifted toward those of normal rat slow motor units.

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Fine Structure of Motor Endplate in Red, White and Intermediate Fibers of Mammalian Fast Muscle

Cited by 18 publications

References 1 publication

Direct correlation of histochemical profile to the ultrastructure of single myofibers and their neuromuscular junctions from a mixed muscle

Direct correlation of histochemical profile to the ultrastructure of single myofibers and their neuromuscular junctions from a mixed muscle

Morphology of the Nerve Terminals of Laryngeal Muscles in the Japanese Monkey (Macaca fuscata)

Functional and structural changes of rat plantaris motoneurons following compensatory hypertrophy of the muscle

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