2018
DOI: 10.1364/boe.9.003883
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Finite-difference time-domain analysis of increased penetration depth in optical coherence tomography by wavefront shaping

Abstract: Multiple scattering in turbid media inhibits optimal light focusing and thus limits the penetration depth in optical coherence tomography (OCT). However, the effects of multiple scattering in a turbid medium can be systematically controlled by shaping the incident wavefront. The authors utilize the reciprocity of Maxwell's equations and finite-difference time-domain numerical analysis to investigate the ultimate performance bounds of wavefront shaping-OCT under ideal and realistic configurations and compare th… Show more

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Cited by 9 publications
(4 citation statements)
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“…For instance, DMD patterns with lower spatial frequencies are used to correct aberrations by increasing the fringe period and decreasing the filtering aperture. Laser processing 14 , optoacoustic microscopy 19 or optical coherence tomography 56 require increased accuracy and high spatial resolution, which can be achieved by increasing the filtering aperture and decreasing the fringe period of binary hologram. In the case when the target wavefront poses a slow variation of amplitude and phase distributions, e.g., cells or intracellular organelles, quantization of modulated complex wave becomes important.…”
Section: Discussionmentioning
confidence: 99%
“…For instance, DMD patterns with lower spatial frequencies are used to correct aberrations by increasing the fringe period and decreasing the filtering aperture. Laser processing 14 , optoacoustic microscopy 19 or optical coherence tomography 56 require increased accuracy and high spatial resolution, which can be achieved by increasing the filtering aperture and decreasing the fringe period of binary hologram. In the case when the target wavefront poses a slow variation of amplitude and phase distributions, e.g., cells or intracellular organelles, quantization of modulated complex wave becomes important.…”
Section: Discussionmentioning
confidence: 99%
“…For instance, DMD patterns with lower spatial frequencies are used to correct aberrations by increasing the fringe period and decreasing the filtering aperture. Laser processing 14 , optoacoustic microscopy 19 or optical coherence tomography 54 require increased accuracy and high spatial resolution, which can be achieved by increasing the filtering aperture and decreasing the fringe period of binary hologram. In the case when the target wavefront poses a slow variation of amplitude and phase distributions, e.g., cells or intracellular organelles, quantization of modulated complex wave becomes important.…”
Section: Discussionmentioning
confidence: 99%
“…Laser processing or lithography objectives 11,14 require increased accuracy and high spatial resolution, which can be achieved by increasing the filtering aperture and decreasing the fringe period of binary hologram. High spatial resolution is also required in imaging applications such as optoacoustic microscopy 19 or optical coherence tomography 45 . However, as we have demonstrated in Subsection 3.1, reduction in the binary pattern carrier frequency results in an increase of phase and amplitude quantization.…”
Section: Discussionmentioning
confidence: 99%