Finite Element Modelling and Experimental Validation of the Enamel Demineralisation Process at the Rod Level

Salvati, Enrico; Besnard, Cyril; Harper, Robert A.; Moxham, Thomas; Shelton, Richard M.; Landini, Gabriel; Korsunsky, Alexander M.

doi:10.1016/j.jare.2020.08.018

Cited by 14 publications

(19 citation statements)

References 28 publications

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“…In silico investigations, such as musculoskeletal modeling [13] and finite-element simulation [14] , [15] , have become an important tool in advanced scientific research. For analysis of bruxism, an in silico investigation allows for the investigation of TMJ loading and the controlled alteration of a single variable, while keeping the rest of the morphology stable and are therefore one of the few tools appropriate for an investigation of the potential connection between TMJ stress and tooth morphology.…”

Section: Introductionmentioning

confidence: 99%

Effect of facet inclination and location on TMJ loading during bruxism: An in-silico study

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Piehslinger

et al. 2022

Journal of Advanced Research

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Section: Introductionmentioning

confidence: 99%

Effect of facet inclination and location on TMJ loading during bruxism: An in-silico study

Sagl

Schmid-Schwap

Piehslinger

et al. 2022

Journal of Advanced Research

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“…( b ) Modelling results showing applied stress as a function of lattice strain in enamel, and in comparison to WAXS and SAXS datasets (adapted from [ 442 ], license accessed on 30 March 2023). ( c ) Synchrotron tomography data of demineralised human enamel used to obtain the demineralised volume and geometrical model of enamel with finite element modelling of the demineralised front (adapted from [ 327 ], license accessed on 30 March 2023). ( d ) Tomography of primate tooth and evaluation of the tooth displacement from unloading to loading (adapted from [ 597 ] with permission.…”

Section: Synchrotron (Circular Particle Accelerator)mentioning

confidence: 99%

“…Using this technique, the lesion was observed, as well as the striae of Retzius, with the details of the mineral concentration showing a visualisation of the surface layer more mineralised than the lesion [ 175 ]. A higher resolution was obtained for the study of caries, and reconstructed data were obtained with a voxel size of 325 nm on different regions of carious enamel (advanced enamel caries and less advanced early enamel caries), as well as enamel with artificial demineralisation [ 39 , 57 , 319 , 327 ] (for more details, see Besnard et al [ 57 ]). In addition to structural visualisation, some parameters were measured from the tomography data, such as the thickness of the lesion, Euclidian distance between voids, and Feret’s diameter of the lesion, adding details about the characterisation of carious enamel, see [ 39 , 57 ] for additional details.…”

Section: Synchrotron (Circular Particle Accelerator)mentioning

confidence: 99%

“…( a5 ) Pathways of the rods from a carious enamel (adapted from [ 39 ], license accessed on 30 March 2023). ( a6 ) Three-dimensional rendering of artificially demineralised enamel and cracking (adapted from [ 327 ], license accessed on 30 March 2023). ( a7 ) Three-dimensional rendering of human dentine and cracking (adapted from [ 359 ] with permission.…”

Section: Synchrotron (Circular Particle Accelerator)mentioning

confidence: 99%

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Synchrotron X-ray Studies of the Structural and Functional Hierarchies in Mineralised Human Dental Enamel: A State-of-the-Art Review

et al. 2023

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Hard dental tissues possess a complex hierarchical structure that is particularly evident in enamel, the most mineralised substance in the human body. Its complex and interlinked organisation at the Ångstrom (crystal lattice), nano-, micro-, and macro-scales is the result of evolutionary optimisation for mechanical and functional performance: hardness and stiffness, fracture toughness, thermal, and chemical resistance. Understanding the physical–chemical–structural relationships at each scale requires the application of appropriately sensitive and resolving probes. Synchrotron X-ray techniques offer the possibility to progress significantly beyond the capabilities of conventional laboratory instruments, i.e., X-ray diffractometers, and electron and atomic force microscopes. The last few decades have witnessed the accumulation of results obtained from X-ray scattering (diffraction), spectroscopy (including polarisation analysis), and imaging (including ptychography and tomography). The current article presents a multi-disciplinary review of nearly 40 years of discoveries and advancements, primarily pertaining to the study of enamel and its demineralisation (caries), but also linked to the investigations of other mineralised tissues such as dentine, bone, etc. The modelling approaches informed by these observations are also overviewed. The strategic aim of the present review was to identify and evaluate prospective avenues for analysing dental tissues and developing treatments and prophylaxis for improved dental health.

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“…Optical changes (white spot lesions) occur due to the increased pore spaces between the thinned rods, which modify the refractive qualities of the enamel [12]. Simulating enamel demineralization is a complex task, and some of the steps can be accomplished using digital instruments, as in the finite elements method [13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

An Evaluation of the Demineralizing Effects of Various Acidic Solutions

et al. 2021

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The purpose of this study was to evaluate which of the techniques and acids included in this in vitro research can induce artificial caries lesions in the most natural way. White spot lesions were created using six different demineralizing solutions in liquid form (lactic acid; orthophosphoric acid; formic acid; and an acid solution that contains calcium chloride, sodium phosphate and acetic acid) and gel form (hydrochloric acid and orthophosphoric acid). Radiographs, photographs and readings with a DIAGNODent™ pen, VITA Easyshade and a scanning electron microscope (SEM) were made in the initial situation, after 30 min, 1 h, 24 h and 96 h of demineralization. The total color change (ΔE) values in most cases presented statistically significant differences. SEM images showed different aspects of the enamel surface for each type of acid. Only in the case of exposed dentine did the DIAGNODent™ pen record significant differences. There was no noticeable radio-translucency of the teeth treated for a short period of time, but after 24 h, the absence of enamel and major demineralization of dentine were visible. Acids in the liquid state can penetrate and demineralize dental structures deeper than those that are more viscous. This study should be repeated with a protocol that includes remineralization. Using weaker acids would be another direction that could lead to more interesting findings.

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Finite Element Modelling and Experimental Validation of the Enamel Demineralisation Process at the Rod Level

Abstract: Graphical abstract

Cited by 14 publications

References 28 publications

Effect of facet inclination and location on TMJ loading during bruxism: An in-silico study

Effect of facet inclination and location on TMJ loading during bruxism: An in-silico study

Synchrotron X-ray Studies of the Structural and Functional Hierarchies in Mineralised Human Dental Enamel: A State-of-the-Art Review

An Evaluation of the Demineralizing Effects of Various Acidic Solutions

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