Finite element simulation and integration of CEM43 °C and Arrhenius Models for ultrasonic-assisted skull bone grinding: A thermal dose model

Babbar, Atul; Jain, Vivek; Gupta, Dheeraj; Agrawal, Deepak

doi:10.1016/j.medengphy.2021.01.008

Medical Engineering & Physics

2021

DOI: 10.1016/j.medengphy.2021.01.008

|View full text |Cite

Finite element simulation and integration of CEM43 °C and Arrhenius Models for ultrasonic-assisted skull bone grinding: A thermal dose model

Atul Babbar

Vivek Jain

Dheeraj Gupta

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2022

2024

Publication Types

Select...

Article6

Relationship

Self Cite0

Independent6

Authors

Journals

Cited by 20 publications

(1 citation statement)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…20,21 It represents the amount of time that tissue has been exposed to temperatures of 43°C that causes thermal damage. 22 Thermal damage thresholds (TDTs) are temperature-time combinations that result in a specific level of tissue damage. 23 These are determined experimentally and are specific to the tissue type.…”

mentioning

confidence: 99%

Preclinical assessment of a noncooled MR thermometry–based neurosurgical laser therapy system

Singh,

Osswald,

Rossman

et al. 2024

Journal of Neurosurgery

View full text Add to dashboard Cite

OBJECTIVE MRI-guided laser interstitial thermal therapy (MRgLITT) has recently gained interest as an ablative stereotactic procedure for intractable epilepsy, movement disorders, and brain tumors. Conventionally, a LITT system consists of a laser generator and cooled laser applicator, which is a fiber optic core surrounded by a sheath through which cooled fluid is pumped. However, this footprint can make the system bulky and nonmobile, limit the maximum depth of targeting, and increase the chances of breakdown. Herein, the authors conduct a preclinical assessment of a noncooled MRgLITT system in a porcine model. METHODS Three-tesla MRI was used to guide the in vivo placement of noncooled laser applicators in the porcine brain. The study consisted of a survival arm and terminal arm. The laser was activated at a power of 4–7 W for ≤ 180 seconds. Temperature changes were monitored using the MR thermometry software ThermoGuide in the survival arm (n = 5) or both ThermoGuide software and adjacently inserted thermal probes in the terminal arm (n = 3). Thermal damage was determined by the software using the temperature-time relationship of cumulative equivalent minutes at 43°C (CEM43). Temperatures calculated by the software were compared with those recorded by the temperature probes. The dimensions of thermal damage thresholds (TDTs; 2–9, 10–59, 60–239, ≥ 240 CEM43 isolines) given by MR thermometry were compared with the dimensions of irreversible damage on histopathological analysis. RESULTS There was a strong correlation between temperature recordings by ThermoGuide and those by thermal probes at both 4 mm (r = 0.96) and 8 mm (r = 0.80), with a mean absolute error of 0.76°C ± 2.13°C and 0.17°C ± 1.65°C at 4 and 8 mm, respectively. The area of 2–9 CEM43 was larger than the area of irreversible damage seen on histopathological analysis. The dimensions of the 10 and 60 CEM43 correlated well with dimensions of the lesion on histopathological analysis. A well-defined border (≤ 1 mm) was observed between the area of irreversible damage and healthy brain tissue. CONCLUSIONS This preclinical assessment showed that the noncooled LITT system was able to precisely reach the target and create well-defined lesions within a margin of safety, without any adverse effects. MR thermometry software provided an accurate near-real-time temperature of the brain tissue, and dimensions of the lesion as visualized by the software correlated well with histopathological findings. Further studies to test the system’s efficacy and safety in human subjects are in progress.

show abstract

mentioning

confidence: 99%

Preclinical assessment of a noncooled MR thermometry–based neurosurgical laser therapy system

Singh,

Osswald,

Rossman

et al. 2024

Journal of Neurosurgery

View full text Add to dashboard Cite

show abstract

Integrating 3D Printed Grinding Tools and Closed‐Loop Temperature Management for Optimal Surgical Outcomes

Wang,

Li,

Liu

et al. 2024

Adv Materials Technologies

View full text Add to dashboard Cite

Grinding is a commonly employed surgical technique for the partial removal of bone. However, the grinding process often generates excessive heat at the interface, leading to localized temperature raise. This can result in irreversible damage to not only the bone but also surrounding tissues, such as nerves. Existing devices rely on the continuous application of coolant to mitigate temperature rise. With the rate and location of coolant deposition being primarily empirical, the current process brings potential risks to patients. In this study, a novel grinding device capable of continuously monitoring grinding temperatures and applying coolant precisely when needed is designed. Utilizing additive manufacturing techniques, a customized grinding tool head equipped with embedded temperature sensors and coolant channels is successfully created. This innovation has enabled the development of an intelligent closed‐loop device that provides precise temperature control during surgery. The device effectively maintains the grinding surface temperature within the user‐defined range, with a latency of less than 1 s. Furthermore, the design ensures that the coolant spray outlets remain unobstructed by debris during grinding and effectively removes debris at the interface, reducing the risk of potential complications, such as bone hyperplasia.

show abstract

Machining of ceramic materials: a state-of-the-art review

Sharma

Babbar

Tian

et al. 2022

Int J Interact Des Manuf

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Finite element simulation and integration of CEM43 °C and Arrhenius Models for ultrasonic-assisted skull bone grinding: A thermal dose model

Cited by 20 publications

References 53 publications

Preclinical assessment of a noncooled MR thermometry–based neurosurgical laser therapy system

Preclinical assessment of a noncooled MR thermometry–based neurosurgical laser therapy system

Integrating 3D Printed Grinding Tools and Closed‐Loop Temperature Management for Optimal Surgical Outcomes

Machining of ceramic materials: a state-of-the-art review

Contact Info

Product

Resources

About