For better studying the relationship between the rifts and deep structure, a detailed P-wave velocity structure under eastern Tibet has been modeled using 4767 arrival times from 169 teleseismic events recorded by 51 portable stations. In horizontal slices through the model, a prominent low-velocity anomaly was detected under the rifts from the surface to a depth of ~250 km; this extends to a depth of ~400 km in the vertical slice. This low-velocity anomaly is interpreted as an upper mantle upwelling. The observations made provide seismic evidence for the formation of north-south trending rifts. East of the low-velocity anomaly, a clear high-velocity anomaly is found between depths of 40 and 200 km. Due to its shallow depth, we suggest that it consists of materials from an ancient continental closure rather than the Indian Plate. From depths of 250 to 400 km, a high-velocity anomaly appears to the south of the Jiali Fault. This anomaly may correspond to the northern edge of the Indian Plate that detached from the surface under the Himalayan block. We suggest that the Indian Plate underthrusts no further than the Jiali Fault in eastern Tibet. The Tibetan Plateau is the world's highest altitude area and a very important region for the geosciences. Since the plateau was formed by the collision of the Indian and Eurasian plates about 50 Ma ago [1] and the subsequent postcollisional intra-continental deformation, strong structural distortion, lithospheric thickening, uplift of the plateau and development of the Himalayan mountains has occurred in this area. Although the Indus-Tsangpo, Bangong-Nujiang and Jinsha River sutures provide some evidence of Tethyan evolution, the precise relationships between the north-south trending structures of southern Tibet and the deep structure of the region are still not clear. Are they grabens [2] or deep fractures? Undoubtedly, these north-south trending structures are the most prominent surface feature in southern Tibet, but their formation mechanism and their relationships with shallow and deep structure [3] are not obvious. Resolving these problems will provide a way to better study the formation and evolution of the Tibetan Plateau.To study the uplift mechanism of the Tibetan Plateau, international exploration projects such as the INDEPTH, Hi-CLIMB and ANTILOPE projects have been undertaken. These projects have provided extensive seismic data sets that can be used to investigate deep structure in this area [4][5][6][7].In the last 20 years, much seismic research has been carried out in the Tibetan Plateau facilitated by the rapid development of seismometer technology. Surface wave investigations suggest that the entire plateau is underlain by a relatively cold lithospheric mantle [8]. Applications of travel time techniques, Zhou [9] have shown that the Indian Plate underthrusts the whole plateau. Other research has found that relatively low S-wave velocities occur in the upper mantle of central and northern Tibet [10,11]. The work of Chen [12] supports the existence of strong ...