From empirically determined values of some of the characteristic constants associated with homogeneous nuclear matter at saturation and subsaturation densities, within the framework of a Skyrme-inspired energy density functional, we construct an equation of state (EoS) of nuclear matter.This EoS is then used to predict values of density slope parameters of symmetry energy L(ρ), isoscalar incompressibility K(ρ), and a few related quantities. The close consonance of our predicted values with the currently available ones for the density dependence of symmetry energy and incompressibility gleaned from diverse approaches offers the possibility that our method may help in settling their values in tighter bounds. Extrapolation of our EoS at supranormal densities shows that it is in good harmony with the one extracted from experimental data.