In this paper, we present a novel spacecraft attitude adaptive tracking control strategy that addresses the challenges posed by unknown inertia parameters, bounded unstructured uncertainties, and various actuator faults. To mitigate the adverse effects of these multiple uncertainties, our proposed control algorithm utilizes a simple tracking‐error feedback and compensation term, which only requires two adaptive parameters. This approach ensures asymptotic tracking convergence by employing an infinitely integrable inequality that incorporates saturation functions. As a result, the complexity of controller design and computational burden are significantly reduced. Finally, several numerical simulations are conducted to validate the feasibility and superiority of our proposed controller.