In this paper, a prescribed-time adaptive H ∞ cooperative strategy with novel prescribed performance and input quantization based on a leader state observer is proposed for uncertain multiple robot manipulators. First, a novel prescribed performance function is introduced into the asymmetric log-type barrier Lyapunov function, which can limit angle errors and reduce the loss of communication resources among multiple robot manipulators. Second, a new prescribed-time leader state estimation observer is proposed to estimate the leader's state information and pass it to the other followers without acceleration information. Third, a prescribed-time adaptive command filter is designed to solve the ''explosion of the complexity'' problem and improves the convergence performance of the control system. Fourth, an adaptive prescribed-time H ∞ cooperative controller with novel prescribed performance and input quantization is designed. Finally, simulation examples are presented to evaluate the stability of the proposed control system.INDEX TERMS Prescribed-time H ∞ control, novel prescribed performance, asymmetric log-type barrier Lyapunov function, prescribed-time leader state estimation observer, prescribed-time adaptive command filter, multiple robot manipulators.