“…[3][4][5][6][7] Several methods are known for the synthesis of β-amino ketones from the ring opening of aziridines. A literature survey shows the few reducing agents, including Raney nickel in ethanol, 8 Pearlman's catalyst [Pd(OH) 2 /C], 9 Adam's catalyst (PtO 2 /HCO 2 H), 10 sodium borohydride, 11 tributyltin hydride, 12 poly(methylhydrosiloxane) (PMHS), 13 silyllithium reagents, 14 magnesium 15 and lithium 16 metal reagents, titanium tetraiodide, 17 samarium(II) iodide 18 and visible-light photoredox ruthenium catalysts, 19 for the reductive ring opening of aziridines. None of these methods, however, result in a direct reduction reaction of N-H aziridines to give derivatives of β-carbamato ketones.…”