2019
DOI: 10.17235/reed.2019.5830/2018
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First approaches for the transplantation of hepatocytes from Wistar rat preneoplastic livers into healthy recipients

Abstract: Background: the shortage of donors of hepatocyte transplantation therapy led to the use of so-called marginal donors. Some donors may have a hepatic illnesses that is associated with hepatic preneoplasia with foci of altered hepatocytes (FAH). Aims: to determine whether recipients developed FAH upon transplantation with hepatocytes from a preneoplastic liver and whether FAH progresses to a preneoplastic hepatocyte-derived tumor (PHDT), up to 60 days after transplantation. Material and methods: male Wistar adul… Show more

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