First Case of Successful Implantation and Live Birth after Double Trophectoderm Biopsy before and after Vitrification on the Same Cohort of Blastocyst

Abstract

Introduction:To report the first case of live birth after double trophectoderm biopsy before and after vitrification on the same cohort of blastocyst in our knowledge.Design: Case report. Patient:A 36-year-old female with a history of 13 years of active married life for treatment of infertility.Main outcome measure: Live birth after double trophectoderm biopsy.Results: Double biopsy pre-and postvitrification and its positive outcome. Conclusion:Preimplantation genetic screening and diagnosis (PGS/PGD), though an invasive procedure on the embryos, when done meticulously would not dampen the implantation potential of the embryo and second biopsy could be a feasible option to salvage embryos with inconclusive or suspected falsepositive PGS/PGD reports.