First demonstration of 3-D lymphatic mapping in breast cancer using freehand SPECT

Wendler, Thomas; Herrmann, Ken; Schnelzer, Andreas; Lasser, Tobias; Traub, Joerg; Kutter, O; Ehlerding, Alexandra; Scheidhauer, Klemens; Schuster, Tibor; Kiechle, Marion; Schwaiger, Markus; Navab, Nassir; Ziegler, Sibylle; Buck, Andreas K.

doi:10.1007/s00259-010-1430-4

Cited by 155 publications

(100 citation statements)

References 18 publications

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“…3-D navigation devices that display the location of the sentinel lymph node three-dimensionally on a screen are currently being tested [180]. The traceability of the sentinel lymph node may be enhanced by immediately preoperative injection of a lymph vessel permeating dye (Patent Blue V) at the tumor site, thus exposing lymphatic pathways and dyeing the sentinel lymph node blue [181,182].…”

Section: Gcpmentioning

confidence: 99%

Malignant Melanoma S3‐Guideline “Diagnosis, Therapy and Follow‐up of Melanoma”

Pflugfelder

Kochs

Blum

et al. 2013

J Deutsche Derma Gesell

181

148

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Section: Gcpmentioning

confidence: 99%

Malignant Melanoma S3‐Guideline “Diagnosis, Therapy and Follow‐up of Melanoma”

Pflugfelder

Kochs

Blum

et al. 2013

J Deutsche Derma Gesell

181

148

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“…The co-registration method used was similar to a previously published method [10]. The affine transformation and other image conversions were performed with open-source program suites (ImageMagick image toolkit).…”

Section: Marker-free Photo-gamma Fusion Lymphoscintigraphy (Pgfls)mentioning

confidence: 99%

Photo-Guided Sentinel Node Mapping in Breast Cancer Using Marker-Free Photo-Gamma Fusion Lymphoscintigraphy

Lee¹,

Chun²,

Ha³

et al. 2012

Nucl Med Mol Imaging

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Purpose Photo-gamma fusion lymphoscintigraphy (PGFLS) was developed by overlying a conventional planar gamma image on a photograph for the guidance of sentinel node biopsy. The feasibility and accuracy of PGFLS was assessed in breast cancer patients. Methods A digital camera and a gamma camera were coordinated to obtain photograph and gamma images from the same angle. Using the distance to the object and calibration acquisition with a flat phantom and radioactive markers, PGFLS was performed both in phantom and in patients without fiducial markers. Marker-free PGFLS was verified using flat phantom, anthropomorphic phantom with markers simulating sentinel nodes and breast cancer patients. In addition, the depth of the radioactive marker or sentinel node was calculated using two gamma images taken at right angles. The feasibility and accuracy of PGFLS were assessed in terms of mismatch errors of co-registration and depth with reference to the data from SPECT/CT.

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“…In this issue, Wendler et al introduce an ingenious device combining a spatial localization system and two tracking targets to be fixed on a gamma probe and on the patient [3]. The localization system consists of an optical camera and an infrared localization device.…”

Section: Towards Intraoperative 3-d Imagingmentioning

confidence: 99%

“…This device combines acoustic signals with 3-D imaging for the localization of the sentinel node in the operating room. This innovative tool may solve various limitations of the current generation of probes [3].…”

mentioning

confidence: 99%