2024
DOI: 10.3390/pharmaceutics16020262
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First Description of Marinoquinoline Derivatives’ Activity against Toxoplasma gondii

Luiza Tamie Hirata Diethelm,
Amanda Bruno da Silva Bellini Ramos,
Giovanna Braga de Lorena
et al.

Abstract: Toxoplasmosis is a globally prevalent zoonotic disease with significant clinical implications, including neurotoxoplasmosis, a leading cause of cerebral lesions in AIDS patients. The current pharmacological treatments for toxoplasmosis face clinical limitations, necessitating the urgent development of new therapeutics. Natural sources have yielded diverse bioactive compounds, serving as the foundation for clinically used derivatives. The exploration of marine bacteria-derived natural products has led to marino… Show more

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