First-episode schizophreniform disorder: comparisons with first-episode schizophrenia

Zarate, Carlos A.; Tohen, Mauricio; Land, Michelle L.

doi:10.1016/s0920-9964(00)00031-1

Cited by 42 publications

(11 citation statements)

References 10 publications

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“…Follow-up rates in our study were not high but within the range reported in an international study [29] , which is due to the very nature of the disease. The diagnostic shift from schizophreniform disorder and psychosis not otherwise specified to schizophrenia in 15 cases over time is in keeping with a study on the long-term course of schizophrenia and schizophreniform disorder [79] . Antipsychotic medication was not standardised but restricted to atypical compounds after a maximum of a 2-week treatment with typical antipsychotics and chosen according to the patients' individual needs -pharmacotherapy was aimed at symptom reduction with minimal side-effects, and indeed sideeffects were rare.…”

Section: Strengths and Limitationssupporting

confidence: 71%

One-Year Outcome and Its Prediction in First-Episode Schizophrenia – A Naturalistic Study

Bachmann¹,

Bottmer

Schröder

2007

Psychopathology

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Background: The literature suggests that the early course of schizophrenia is a strong predictor of long-term outcome. We sought to test this notion in a sample of first-episode patients. Sampling and Methods: Forty patients with a first episode of DSM-IV diagnoses of schizophrenia, schizoaffective, or schizophreniform disorder were assessed with well-established instruments such as the Positive and Negative Syndrome Scale and the Strauss-Carpenter Scale. Reassessment was performed 14 months later and included the Global Assessment of Functioning Scale in addition to the aforementioned instruments and a psychiatric interview. Regression analyses for the Global Assessment of Functioning Scale and symptomatology were used to identify outcome predictors. Results: At follow-up, 27 patients (67.5%) were in remission. Women’s outcome was significantly better with respect to intimate relationships and domiciliary independence. Although symptomatology of the whole group remained stable during the follow-up period, a subgroup of patients experienced a significant decrease in symptom levels whereas symptoms increased in another subgroup. The most important predictor of outcome was compliance with atypical antipsychotic medication during the follow-up period. Conclusions: These results suggest that there is a prognostic divide early in the course of the disease, that compliance with medication is of overriding importance towards 1-year outcome, and that for the individual patient the question of chronicity may be answered very early in the course of the disease.

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Section: Strengths and Limitationssupporting

confidence: 71%

One-Year Outcome and Its Prediction in First-Episode Schizophrenia – A Naturalistic Study

Bachmann¹,

Bottmer

Schröder

2007

Psychopathology

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“…In his 1994 review, Strakowski questioned the validity of a diagnosis of schizophreniform disorder (Strakowski, 1994). Since then, one study found frequent diagnostic change to schizophrenia 2 years after index episode (Zarate et al 2000). The authors concluded that the diagnosis of schizophreniform disorder has no value and should be discarded.…”

Section: Discussionmentioning

confidence: 99%

The concordance of ICD-10 acute and transient psychosis and DSM-IV brief psychotic disorder

et al. 2002

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“…Follow‐up studies of first‐episode psychoses have revealed that diagnostic stability is highest for manic psychoses 7 . Schizophrenia, schizoaffective disorders and bipolar disorders have also been found to be stable, whereas schizophreniform disorders, drug‐induced psychoses and psychosis not otherwise specified (NOS) are the least stable 8–12 …”

Section: Introductionmentioning

confidence: 99%

Social and symptomatic outcomes of first‐episode bipolar psychoses in an early intervention service

MacMillan

Howells

Kale

et al. 2007

Early Intervention Psych

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Aim: We aimed to establish the relative proportions of all diagnoses in people aged 14-35 years presenting to an early intervention in psychosis service, and to compare demographic variables, symptoms and outcomes between the bipolar psychoses and other psychoses at 3-6 months and 1 year post referral. Methods:Prospective 3-to 6-month diagnostic and symptomatic assessments were carried out. Diagnoses were established using the Diagnostic Interview for Psychoses -Diagnostic Module. Symptoms and outcomes were assessed using standardized instruments at 3-6 months and 1 year. Bipolar diagnoses were grouped together in a bipolar group (n = 16) and compared with all other diagnoses, in a non-bipolar group (n = 62). Parallel analysis was carried out using groups of lifetime elevated, expansive or irritable mood (n = 32) and no lifetime elevated, expansive or irritable mood (n = 46).Results: Bipolar disorders account for 20.5% of all new presentations to our service. Differences in outcomes over the range of psychotic diagnoses relate to early presence of negative symptoms. Psychoses with bipolar diagnoses or lifetime elevated, expansive or irritable mood showed lower rates of negative symptoms than other psychoses and had a higher quality of life and higher function at 3-6 months and 1 year. Conclusions:Planning for future early intervention services should take the high rate of affective psychoses and their need for diagnosisspecific, evidence-based treatments into account. Lifetime elevated, expansive or irritable mood may predict improved outcomes in early psychoses, possibly mediated by lower levels of negative symptoms.

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First-episode schizophreniform disorder: comparisons with first-episode schizophrenia

Cited by 42 publications

References 10 publications

One-Year Outcome and Its Prediction in First-Episode Schizophrenia – A Naturalistic Study

One-Year Outcome and Its Prediction in First-Episode Schizophrenia – A Naturalistic Study

The concordance of ICD-10 acute and transient psychosis and DSM-IV brief psychotic disorder

Social and symptomatic outcomes of first‐episode bipolar psychoses in an early intervention service

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