First evidence of occupational asthma to argan powder in a cosmetic factory

Paris, Christophe; Hérin, Fabrice; Penven, Emmanuelle; Thaon, Isabelle; Richard, Christelle; Jacquenet, S.; Barbaud, A.; Mathias, Poussel

doi:10.1111/all.12811

Cited by 10 publications

(3 citation statements)

References 8 publications

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“…Levels of specific IgE against milk compounds such as caseins, α-lactalbumin and β-lactoglobulin could be also measured as confounding factors. Moreover, it is well known that occupational exposure to dust in general and/or microorganisms is often deleterious to health (Roussel et al 2012; van Kampen et al 2012; Dorribo et al 2015; Bittner et al 2016; Paris et al 2016). We recommend the implementation of technical and/or organisational preventive measures to avoid or reduce this exposure (both exposure to milk powder and LAB).…”

Section: Resultsmentioning

confidence: 99%

Lack of evidence of IgE allergic sensitisation from working with lactic acid bacteria in the dairy foods industry

Barrera

Reboux

Laboissière

et al. 2018

Journal of Dairy Research

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This research communication aimed to evaluate the level of immunoglobulin E from lactic acid bacteria (LAB) that are used in dairy industries. Previous studies have demonstrated that workers report symptoms of irritation and are frequently IgG-sensitised to LAB. Workers (n = 44) from a probiotic production unity and the control lab were seen by a medical practitioner and responded to an occupational questionnaire. Specific IgE by the DELFIA® technique against 6 strains of LAB were measured on 44 exposed workers and 31 controls sera. Levels of specific IgE were low and no difference was observed between the two groups. This lack of IgE response could be explained by a healthy worker effect, an efficient implementation of personal protective equipment or by an absence of allergic mechanisms to account for the self-reported irritative symptoms. Despite the high concentrations of LAB, preventive measures are effective enough to guarantee no allergic effect and to prevent other adverse health effects. The implementation of preventive measures to avoid or reduce exposure to dust of LAB, and more generally to milk powder, is recommended in all dairy industry.

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Section: Resultsmentioning

confidence: 99%

Lack of evidence of IgE allergic sensitisation from working with lactic acid bacteria in the dairy foods industry

Barrera

Reboux

Laboissière

et al. 2018

Journal of Dairy Research

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“…Two cases of allergic dermatitis have been described to date [7]. Cases of rhinitis, conjunctivitis related to the smell of Argan oil, and cases of epigastralgia and hypersalivation upon ingestion of Argan oil [8]. It should be mentioned that two cases of acute hypersensitivity pneumonitis have been reported in cosmetic workers exposed to Argan powders [9].…”

Section: Discussionmentioning

confidence: 99%

Allergy to Argan Oil Confirmed by Oral Challenge Test in Children: Case Report

Aminou

Mahraoui

2023

AJPR

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Aims: The prevalence of allergy to Argan oil is increasing over the years. It manifests itself in an extremely polymorphous way and responds to all possible routes of exposure: ingestion, contact or inhalation. The provocation test remains the key examination to confirm an allergy to Argan oil. Presentation of Case: We report the observation of a six-year-old girl presenting with immediate urticaria after ingestion of argan oil. Discussion: The allergological investigation points to sensitisation of the skin only, with positive prick tests. An oral provocation test was performed and published for the first time to confirm the diagnosis of allergy to argan oil in our patient. Conclusion: Argan is widely used for its benefits in the cosmetic industry and as a food ingredient. Further studies are needed to explore the mechanisms of sensitisation to Argan oil.

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“…The "control" day has two important goals: to check functional stability, which is absolutely necessary for the correct interpretation of changes in FEV 1 , and also to provide a comparison point for any reactions to the tested active agent. Delivery of the occupational agent can be conducted by different ways, depending on the nature of the agent tested, but always as close as possible to the workplace conditions [43,44]. More information on the techniques used for SIC with different occupational agents such as the form and nature of the active and control agents and on methods, quantities, and duration of delivery can be found in the handbook of procedures for SIC testing, available as supplementary material, of the European Respiratory Society Task Force [13,45].…”

Section: Specific Inhalation Challenge (Sic)mentioning

confidence: 99%

Pulmonary Function Testing in Work-Related Asthma: An Overview from Spirometry to Specific Inhalation Challenge

Poussel

Thaon

Penven

et al. 2021

IJERPH

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Work-related asthma (WRA) is a very frequent condition in the occupational setting, and refers either to asthma induced (occupational asthma, OA) or worsened (work-exacerbated asthma, WEA) by exposure to allergens (or other sensitizing agents) or to irritant agents at work. Diagnosis of WRA is frequently missed and should take into account clinical features and objective evaluation of lung function. The aim of this overview on pulmonary function testing in the field of WRA is to summarize the different available tests that should be considered in order to accurately diagnose WRA. When WRA is suspected, initial assessment should be carried out with spirometry and bronchodilator responsiveness testing coupled with first-step bronchial provocation testing to assess non-specific bronchial hyper-responsiveness (NSBHR). Further investigations should then refer to specialists with specific functional respiratory tests aiming to consolidate WRA diagnosis and helping to differentiate OA from WEA. Serial peak expiratory flow (PEF) with calculation of the occupation asthma system (OASYS) score as well as serial NSBHR challenge during the working period compared to the off work period are highly informative in the management of WRA. Finally, specific inhalation challenge (SIC) is considered as the reference standard and represents the best way to confirm the specific cause of WRA. Overall, clinicians should be aware that all pulmonary function tests should be standardized in accordance with current guidelines.

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First evidence of occupational asthma to argan powder in a cosmetic factory

Abstract: High-level exposure to argan powder should be considered to be a potential cause of IgE-mediated allergy, and workers handling argan powder should be carefully investigated.

Cited by 10 publications

References 8 publications

Lack of evidence of IgE allergic sensitisation from working with lactic acid bacteria in the dairy foods industry

Lack of evidence of IgE allergic sensitisation from working with lactic acid bacteria in the dairy foods industry

Allergy to Argan Oil Confirmed by Oral Challenge Test in Children: Case Report

Pulmonary Function Testing in Work-Related Asthma: An Overview from Spirometry to Specific Inhalation Challenge

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