First Human Demonstration of Cardiac Stimulation With Transcutaneous Ultrasound Energy Delivery

Abstract

The feasibility and safety of pacing usng ultrasound energy has been shown acutely.

Left Ventricular Endocardial Pacing Improves Resynchronization Therapy in Canine Left Bundle-Branch Hearts

“…Finally, endocardial CRT will become more feasible when the technology of leadless pacing becomes available. 20 Clearly, the applicability of endocardial CRT in humans will depend on tools allowing safe and effective long-term LV pacing.…”

Leadless cardiac stimulation: ready to take centre stage?

“…Though these devices showed great promise, it was not until more re cently that the research community and industry have accelerated the development of human leadless pace makers. At first, the concept of leadless devices still required the implantation of an extracardiac genera tor that would transmit wirelessly to an intracardiac receiver, either by ultrasound energy [9][10][11] or mag netic fieldinduction energy [12]. However, since 2012, …”

Cardiac Resynchronization Therapy: Lead Positioning and Technical Advances

“…Ultrasound and magnetic field waves have been used to induce electrical stimulation via an intracardiac receiver electrode (Kapa et al, 2010;Lee et al, 2007). In an animal study Echt et al (Echt et al, 2006) used burst ultrasound energy transmission through the chest to a receiver electrode mounted on a catheter that converted the ultrasound energy to electrical energy sufficient to pace the myocardium.…”