First in human surgical implantation of a leadless pacemaker on the epicardial portion of the right atrial appendage in a patient with a cardiac electronic devices mediated dermatitis

Eltsov, Ivan; Sorgente, Antonio; Asmundis, Carlo de; Meir, Mark La

doi:10.1093/icvts/ivac050

Cited by 4 publications

(3 citation statements)

References 5 publications

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“…Implantable pacemakers, which are traditionally used for human therapies (9,10), are useful for providing programmed electrical stimulation during cardiac electrophysiology studies. However, with the development of highly miniaturized fully implantable pacemakers for rodents (11,12), studies of cardiac electrophysiology can be expanded to transgenic small animal models (13)(14)(15)).…”

Section: Introductionmentioning

confidence: 99%

Wireless, fully implantable cardiac stimulation and recording with on-device computation for closed-loop pacing and defibrillation

et al. 2022

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Monitoring and control of cardiac function are critical for investigation of cardiovascular pathophysiology and developing life-saving therapies. However, chronic stimulation of the heart in freely moving small animal subjects, which offer a variety of genotypes and phenotypes, is currently difficult. Specifically, real-time control of cardiac function with high spatial and temporal resolution is currently not possible. Here, we introduce a wireless battery-free device with on-board computation for real-time cardiac control with multisite stimulation enabling optogenetic modulation of the entire rodent heart. Seamless integration of the biointerface with the heart is enabled by machine learning–guided design of ultrathin arrays. Long-term pacing, recording, and on-board computation are demonstrated in freely moving animals. This device class enables new heart failure models and offers a platform to test real-time therapeutic paradigms over chronic time scales by providing means to control cardiac function continuously over the lifetime of the subject.

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Section: Introductionmentioning

confidence: 99%

Wireless, fully implantable cardiac stimulation and recording with on-device computation for closed-loop pacing and defibrillation

et al. 2022

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“…En el caso de disfunción del nodo sinusal pura con conducción AV intacta, un LP auricular (sin respaldo ventricular) podría ser suficiente. Existe un reporte de caso en el que se ya se implantó un LP para estímulo auricular epicárdico de manera exitosa 46 . Para los pacientes con bloqueo AV y función intacta del nódulo sinusal, un Micra AV puede ser el dispositivo de elección, especialmente con futuras mejoras en la detección y el seguimiento auricular.…”

Section: Lp Auricular Y Bicameralunclassified

Marcapasos sin cables: un reto futurista en estimulación intracardiaca

Fabris,

Olaya,

Betancourt

et al. 2024

RCCAR

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Introducción: Los marcapasos sin cables han revolucionado el campo de la estimulación al reducir su tamaño y hacerlos completamente intracardiacos, lo que disminuye las complicaciones relacionadas con los bolsillos y los cables transvenosos. En este artículo, se revisan los datos disponibles sobre los marcapasos sin cables y se presenta una serie de los primeros 9 pacientes implantados en Colombia. Objetivo: Presentar una serie de 9 casos de implante de marcapasos sin cables, que, hasta abril de 2022, se han realizado en Colombia, y describir las características clínicas de los pacientes intervenidos. Materiales y método: Estudio descriptivo, presentación de serie de casos. Resultados: Se implantaron 9 dispositivos en varias instituciones del país. El promedio de edad de los pacientes fue de 72 años, 77% fueron hombres, con un antecedente de marcapaso previo de hasta un 89% (75% por bloqueo AV completo). La indicación principal para su implante fueron las infecciones recurrentes (66.7%). En ninguno de los casos se presentó complicación inmediata. Conclusiones: Aunque continúa la expansión en cuanto a las indicaciones del marcapasos sin cables, se cuenta con evidencia sólida de viabilidad, seguridad y eficacia tanto a corto como mediano plazo como alternativa en pacientes seleccionados. Consideramos que el implante de marcapasos sin cable en nuestro país ha sido una experiencia exitosa.

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“…For pure sinus node dysfunction with intact AV conduction, an atrial LP (without ventricular backup) could be sufficient. There is a case report in which an epicardial atrial pacing LP was already successfully implanted 46 . For patients with AV block and intact sinus node function, a Micra AV may be the device of choice, especially with future improvements in atrial detection and monitoring.…”

Section: Atrial and Dual-chamber Lpsmentioning

confidence: 99%

Leadless pacemakers: a futuristic challenge in intracardiac pacing

Fabris,

Olaya,

Betancourt

et al. 2024

RCCARE

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Introduction: leadless pacemakers have revolutionized the pacing field by reducing their size and making them completely intracardiac, thus reducing complications related to pockets and transvenous leads. In this article, we review the available data on leadless pacemakers and present a series of the first nine patients implanted in our country. Objectives: to present a series of nine cases implanted in our country so far (April 2022) and describe the clinical characteristics of these patients. Materials and method: a descriptive study, case series presentation. Results: nine devices were implanted in various institutions in the country; the average age of the patients was 72 years, and 77% were men, with a history of previous pacemaker implantation in up to 89% (75% due to complete AV block). The main indication for device implantation was recurrent infections (66.7%). No immediate complications occurred in any of the cases. Conclusions: although the indications for leadless pacing continue to expand, there is solid evidence of its feasibility, safety and efficacy both in the short and medium term as an alternative in selected patients. We consider that leadless pacemaker implantation in our country has been a successful experience.

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First in human surgical implantation of a leadless pacemaker on the epicardial portion of the right atrial appendage in a patient with a cardiac electronic devices mediated dermatitis

Cited by 4 publications

References 5 publications

Wireless, fully implantable cardiac stimulation and recording with on-device computation for closed-loop pacing and defibrillation

Wireless, fully implantable cardiac stimulation and recording with on-device computation for closed-loop pacing and defibrillation

Marcapasos sin cables: un reto futurista en estimulación intracardiaca

Leadless pacemakers: a futuristic challenge in intracardiac pacing

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