First International Conference on Vaginosis: Nonspecific Vaginitis Kristiansand, Norway, April 16–17, 1982

Evaluating the Activity of Neuraminidase in Bacterial Vaginosis Microflora and Imaging Sialic Acid on the Cell Membrane by Boron and Nitrogen Codoped Fluorescent Carbon Dots

“…NEU plays an important role during the spreading processes of many pathogenic viruses and microbes, which can be employed as a predictive marker of microbial infections, such as bacterial vaginosis (BV) associated with anaerobic bacteria. 10 As a result of dysbiosis of the vaginal microbiome, BV is characterized by the depletion of normal lactobacillus-dominant microbiota and overgrowth of anaerobic bacteria including Gardnerella vaginalis, Prevotella sp., Mobiluncus sp., and Mycoplasma hominis. 11−13 NEU produced by the above anaerobic floras promotes the adhesion of bacteria to epithelia, which predisposes women to an increased risk of premature delivery, endometriosis, pelvic inflammatory disease, and vaginal cellulitis.…”