First isolations of KPC-2-carrying ST258 Klebsiella pneumoniae strains in Finland, June and August 2009

Österblad, Monica; Kirveskari, Juha; Koskela, Suvi; Tissari, Päivi; Vuorenoja, K.; Hakanen, Antti; Vaara, Martti; Jalava, Jari

doi:10.2807/ese.14.40.19349-en

Cited by 17 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ESBL-producing microbes can be identified using a chromogenic combination. All non-ESBL-producing bacteria are inhibited by the supplement ( ceftazidime 1.50 mg, cefotaxime 1.50mg , ceftriazone 1.00mg, Aztreonam 1.00mg, fluconazole 5.00 mg additional to 500ml chromogenic media [11].…”

Section: Multi-drug Resistance Of K Pneumoniae Isolatesmentioning

confidence: 99%

“…The phenotypic and genetic features of Klebsiella isolates recovered from healthy and unwell babies showed no change [20] The development and spread of ESBL among Gram-negative bacteria and possible horizontal transfer calls for concern, especially in view of treatment failure, high treatment cost, and consequent discomfort to patients. The early detection of ESBL-producing bacteria carriers is essential to minimize their impact and spread [11].…”

Section: Phenotypic Detection Of β-mentioning

confidence: 99%

See 1 more Smart Citation

Molecular Investigation of mrkA in Klebsiella pneumoniae Isolated from Nosocomial and Community Infection in Diyala Province, Iraq

2022

djps

View full text Add to dashboard Cite

Klebsiella pneumoniae is a pathogen relevant to hospital acquired and community acquired such as urinary tract infections, pneumonia, and wound and burn. It has high levels of antibiotic resistance and capability to produce biofilm. This study included comparing among six antibiotic resistance patterns for the hospital and community acquired infections, and detected biofilm gene (mrkA). Clinical samples were collected from Teach Bagubah Hospital, Al-Batool Maternity and Children Teaching Hospital, and private laboratories in Baqubah/Diyala, Iraq.To investigate antibiotics susceptibility, the Kirby-Bauer disk diffusion method was used to compare between community acquired isolates and hospital acquired isolates. Hospital acquired of K. pneumoniae were less susceptible than community acquired of K. pneumoniae isolates.Both isolates community acquired and hospital acquired were high rates of resistance for βlactam/β -lactamase (Amoxicillin-clavulanate and Ticarcillin-clavulante). Screening and confirmation based on ESBL chromogenic agar are more sensitive than ESBL producers of the double disk synergy test, which were 30% and 60% produce-ESBLs in nosocomial acquired, and 20% and 40% in community acquired, respectively. The results of gel electrophoresis for PCR product using specific primers for mrkA gene prevalence were 83.33% and 66.6% in

show abstract

Section: Multi-drug Resistance Of K Pneumoniae Isolatesmentioning

confidence: 99%

Section: Phenotypic Detection Of β-mentioning

confidence: 99%

Molecular Investigation of mrkA in Klebsiella pneumoniae Isolated from Nosocomial and Community Infection in Diyala Province, Iraq

2022

djps

View full text Add to dashboard Cite

show abstract

Controlling Hospital-Acquired Infection due to Carbapenem-Resistant Enterobacteriaceae (CRE)

Schwaber

Carmeli

Harbarth

2011

Antibiotic Policies

View full text Add to dashboard Cite

Emergence of a colistin-resistant KPC-2-producing Klebsiella pneumoniae ST258 clone in Hungary

Tóth

Damjanova

Puskás

et al. 2010

Eur J Clin Microbiol Infect Dis

104

View full text Add to dashboard Cite

Nine Klebsiella pneumoniae isolates showing non-susceptibility to carbapenems were collected from three centres in the north-eastern region of Hungary. The minimum inhibitory concentrations (MICs) of antibiotics were determined by Etest. The putative production of a carbapenemase was tested by the modified Hodge test. The presence of bla (KPC) genes was verified by polymerase chain reaction (PCR) and sequencing. Furthermore, molecular typing was performed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). All isolates showed extensively drug-resistant (XDR) phenotype, and of these, eight isolates were highly resistant to colistin. The isolates carried bla (KPC-2), bla (SHV-12), bla (TEM-1) and bla (SHV-11). PFGE analysis of the nine KPC-2-producing Hungarian ST258 K. pneumoniae isolates, two KPC-2-producing Norwegian ST258 isolates and 33 CTX-M-15-producing ST11 isolates revealed the existence of one genetic cluster at an 88% similarity level. The overall results of the PFGE clustering, MLST and the presence of SHV-11 in both ST11 and ST258 suggest that this is the first hyperepidemic clonal complex of multidrug-resistant K. pneumoniae, probably CC258/CC340, possibly undergoing worldwide spread.

show abstract

First isolations of KPC-2-carrying ST258 Klebsiella pneumoniae strains in Finland, June and August 2009

Cited by 17 publications

References 0 publications

Molecular Investigation of mrkA in Klebsiella pneumoniae Isolated from Nosocomial and Community Infection in Diyala Province, Iraq

Molecular Investigation of mrkA in Klebsiella pneumoniae Isolated from Nosocomial and Community Infection in Diyala Province, Iraq

Controlling Hospital-Acquired Infection due to Carbapenem-Resistant Enterobacteriaceae (CRE)

Emergence of a colistin-resistant KPC-2-producing Klebsiella pneumoniae ST258 clone in Hungary

Contact Info

Product

Resources

About