First-line antiretroviral treatment failure and associated factors in HIV patients following highly active antiretroviral therapy at the Shashemene Referral Hospital, Oromia region, Ethiopia

Ayeno, Hunduma; Imer, Ahmedyasin

doi:10.5114/hivar.2020.96388

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…In Indonesia, the public health service system was developed to deal with health problems, including health office, PHCs, and community [17]. In order to optimize the role of community in Indonesia to be involved in health activities, community resources, such as integrated health service (Posyandu) with active involvement of health workforce [18] were created to improve ARV program and prevent social problems in the community [19,20].…”

Section: Public/community Health Nursing Activities For Hiv/aids Caring In the Communitymentioning

confidence: 99%

Multi-level intervention for HIV/AIDS caring in Indonesian community

Susanto¹,

Yunanto²,

Rasni³

et al. 2021

HIV & AIDS Review

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Treating the spread of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) needs to be carried out with community participation. Caring community behavior problems require holistic approach for each individual element as well as society related to cultural factors and community contexts, such as norms, relationships, and critical structural factors in strengthening desired outcomes, especially in HIV/AIDS prevention. Some interventions aimed at increasing diversity of participants, and were mostly focused on overcoming individual-level of barriers to research participation. Most of the interventions did not evaluate their effectiveness on increasing the level of trial participation. Overall, there is little focus on interventions aimed at researchers, clinical trials, institutional policy factors, or studies. Therefore, a HIV/AIDS model of intervention is needed that emphasizes the inter-relationship of community elements, with local socio-cultural approaches through multi-level interventions.

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Section: Public/community Health Nursing Activities For Hiv/aids Caring In the Communitymentioning

confidence: 99%

Multi-level intervention for HIV/AIDS caring in Indonesian community

Susanto¹,

Yunanto²,

Rasni³

et al. 2021

HIV & AIDS Review

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Systematic Review and Meta-Analysis of Retention and Disengagement After Initiation on Antiretroviral Therapy in Low- and Middle-Income Countries After the Introduction of Universal Test and Treat Policies

Zheng,

Kileel,

Brennan

et al. 2024

Preprint

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Background: We previously published a systematic review evaluating retention in care after antiretroviral therapy treatment initiation among adults in low- and middle-income countries. We estimated retention at 36 months to be at 74% for studies published from 2008-2013. This review evaluates retention after the implementation of Universal Test and Treat in 2015. Methods: We searched PubMed, ISI Web of Science, Cochrane Database of Systematic Reviews, and EMBASE for studies published between January 1, 2017, to December 31, 2023 and searched conference abstract repositories from AIDS, IAS, and CROI from 2015-2023. Retention for each study was estimated using 1) simple averages and 2) interpolated for missing timepoints through the last reported timepoint. All-cause attrition for all participants who initiated first-line treatment in low- and middle-income countries was estimated. Overall retention rates were estimated using a generalized linear mixed model with a logit distribution using the interpolated data. Results: A total of 65 studies met our criteria for inclusion for the systematic review. Most studies came from Africa with very few from Europe and Asia. Very few studies reported retention past the first 12 months following treatment initiation. Across all studies, we estimated simple average retention with no interpolation of missing timepoints to be 72.6% at 12 months, 73.2%, at 24 months, 59.8% at 36 months, and 49.4% at 48 months. Utilizing a GLMM model, we estimated retention to be 86.0% at 6 months, 80.0% at 12 months, 82.0% at 24 months, 71.0% at 36 months, and 57.0% at 48 months. In comparison, our prior review conducted in 2015, estimated retention rates to be 91.0% at 6 months, 86.0% at 12 months, 79.0% at 24 months, 75% at 36 months, and 69% at 48 months. These results generally reflect retention at the initiating facility and omit the effect of unreported transfers. Conclusions: Retention in care at 36 months was estimated to be between 60% and 71%. Compared to results from our prior review, retention has stayed largely similar in the post-UTT era. Further research evaluating retention in other geographic areas (i.e., Latin America and the Caribbean, Europe, and Asia) is needed.

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First-line antiretroviral treatment failure and associated factors in HIV patients following highly active antiretroviral therapy at the Shashemene Referral Hospital, Oromia region, Ethiopia

Cited by 2 publications

References 6 publications

Multi-level intervention for HIV/AIDS caring in Indonesian community

Multi-level intervention for HIV/AIDS caring in Indonesian community

Systematic Review and Meta-Analysis of Retention and Disengagement After Initiation on Antiretroviral Therapy in Low- and Middle-Income Countries After the Introduction of Universal Test and Treat Policies

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