First-Line Interactive Wound Dressing Update: A Comprehensive Review of the Evidence

Abstract

Wound management is a significant and growing issue worldwide. Knowledge of dressing products and clinical expertise in dressing selection are two major components in holistic wound management to ensure evidence-based wound care. With expanding global market of dressing products, there is need to update clinician knowledge of dressing properties in wound care. Optimal wound management depends on accurate patient assessment, wound diagnosis, clinicians' knowledge of the wound healing process and properties of wound dressings. We conducted a comprehensive review of the physical properties of wound dressing products, including the advantages and disadvantages, indications and contraindications and effectiveness of first-line interactive/bioactive dressing groups commonly used in clinical practice. These include semipermeable films, foams, hydroactives, alginates, hydrofibers, hydrocolloids, and hydrogels. In making decisions regarding dressing product selection, clinicians need to ensure a holistic assessment of patient and wound etiology, and understand dressing properties when making clinical decisions using wound management guidelines to ensure optimal patient outcomes. This review has highlighted there is lack of high quality evidence and the need for future well designed trials.

Sulfated Polysaccharides from Marine Algae as a Basis of Modern Biotechnologies for Creating Wound Dressings: Current Achievements and Future Prospects

“…A few detailed reviews considering the clinical practice and current biotechnological trends, as regards the design features, properties, mechanisms of action, and indications for the use of the main classes of wound dressings made of natural biopolymers, have been published in the dedicated Russian and world's literature in recent years [3,4,12,31].…”

Regenerative Wound Dressings for Skin Cancer

“…However, wound areas larger than 2 cm 2 , wound duration longer that 2 months, and increased wound depth which results in tendon, ligament, or bone exposure are the three main factors which delay or stop the healing process. In this context, research is focused on developing wound dressings not only for protection purposes, but also to promote healing and regeneration processes [ 118 , 119 ]. Therefore, the application of healing-promoting approaches has shown to trigger, accelerate, and enhance wound healing, re-epithelialization, and collagen formation, which subsequently results in reduced scar formation and complications [ 120 , 121 ].…”

“…Moreover, interactive dressings support all the stages involved in the healing process, such as debris removal, granulation tissue formation, and re-epithelialization, while also decreasing exudate formation and preventing bacterial colonization. Among them, hyaluronic acid, collagen, and alginate-based dressings are the most commonly and extensively investigated products [ 25 , 118 ]. These natural polymers are highly advantageous owing to their cell proliferation and growth, tissue regeneration, non-toxicity, minimal inflammatory and immunological response induction characteristics.…”

Diabetic wound infection: A review on microbial population and infection control

“…However, traditional wound dressing failed to provide a moist environment and maintain the pH of wound sites (Boateng et al, 2008). To overcome this problem, many types of modern wound dressing were developed include hydrocolloid, hydrogel, alginate and collagen wound dressing (Dhivya et al, 2015;Weller et al, 2020). Hydrocolloid dressings are composed of hydrocolloid materials such as gelatin, pectin, and carboxymethyl cellulose which provide a moist environment for wound healing and barrier to external microorganisms (Dorner et al, 2009).…”