First live birth after uterine transposition

Ribeiro, Reitan; Anselmi, Maria Cristina; Schneider, Gunther Alex; Furtado, José Pio Rodrigues; Shwareb, Mohamed Gaber Mohamed Abau; Linhares, José

doi:10.1016/j.fertnstert.2023.02.033

Cited by 10 publications

(8 citation statements)

References 22 publications

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“…We report a successful UOT in a patient with rectal cancer. Since 2017, this technique has been proposed as a fertility preservation method for selected patients requiring pelvic radiotherapy for colorectal ( 9 , 14 , 18 ), vaginal ( 12 ), and cervical cancers ( 10 – 12 , 15 , 17 ), intergluteal yolk sac tumors ( 13 ), and iliac myxoid low-grade liposarcoma ( 16 ). A total of 14 cases have been reported in 10 articles ( Table 1 ).…”

Section: Discussionmentioning

confidence: 99%

“…Uterine necrosis after UOT has been reported only once ( 19 ), but the risk of less serious postoperative utero-ovarian functional disorders could not be excluded, even if their potential incidence is currently difficult to predict. Low-molecular-weight-heparin, with or without aspirin, has been administered to mitigate the risk of thrombosis and subsequent utero-ovarian hypoperfusion ( 16 , 26 ). Another potential risk is to move cancer cells from the pelvis to the upper abdomen.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, Ribeiro et al reported the first case of live birth after UOT ( 16 ). This patient, diagnosed with liposarcoma, got spontaneously pregnant 2 years after UOT and had an uneventful pregnancy until 36 weeks of gestation, when she presented preterm labor and underwent a cesarean section, with good maternal and neonatal outcomes ( 16 ). Afterward, Lopez et al reported the case of another live birth following a spontaneous pregnancy after UOT in a patient diagnosed with rectal carcinoma ( 18 ).…”

Section: Discussionmentioning

confidence: 99%

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Utero-ovarian transposition before pelvic radiation in a patient with rectal cancer: a case report and systemic literature review

Huber,

Simonson,

Fournier

et al. 2024

Front. Surg.

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ObjectiveTo describe a case of utero-ovarian transposition (UOT) before pelvic radiation in a patient with rectal cancer and provide a systematic literature review on all reported cases of UOT.MethodsWe performed a prospective collection and revision of clinical, intraoperative, and postoperative data from a patient who underwent UOT. In addition, a systematic review of the literature available to date on all cases of UOT was realized, and 14 patients from 10 articles were included.ResultsWe reported the case of a 28-year-old nulligravida patient who was diagnosed with a low-grade rectal adenocarcinoma and underwent neoadjuvant chemoradiotherapy, followed by transanal total mesorectal excision (TaTME). Before starting neoadjuvant oncological therapies, the patient underwent laparoscopic UOT. The intervention was performed without complications, and the patient received neoadjuvant oncological treatments as planned. TaTME and uterus repositioning were completed six weeks after the end of radiotherapy. No complications were observed during the first 9 postoperative months. Adequate utero-ovarian perfusion was assessed by Doppler ultrasound, cervicovaginal anastomosis appeared to have healed correctly, and the patient experienced menstrual bleeding. Data from the literature review of all reported cases of UOT were presented and discussed.ConclusionsUOT represents a valuable option to preserve fertility in patients requiring pelvic radiotherapy. This study provides additional evidence on the feasibility and safety of performing UOT.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Utero-ovarian transposition before pelvic radiation in a patient with rectal cancer: a case report and systemic literature review

Huber,

Simonson,

Fournier

et al. 2024

Front. Surg.

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“…In addition, it is an option that may allow for these young women to conceive naturally and spontaneously and then carry a full-term pregnancy. 7 Thus, for this case, we would recommend combining different methods of fertility preservation to optimize the chances of a successful pregnancy. The first option would be embryo and oocyte cryopreservation associated with uterine transposition.…”

Section: Dr Ribeiro: Based On the Age Of The Patient And Wishes For F...mentioning

confidence: 99%

Uterine transposition and successful pregnancy in a patient with rectal cancer

Lopez,

Perez Villena,

Guevara Jabiles

et al. 2023

International Journal of Gynecological Cancer

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A 32-year-old woman who complained of intermittent rectal bleeding prior to presentation was seen in the emergency department in an outside facility in March 2019. Medical history was non-contributory. The patient had a prior cesarean section in December 2005. There was no personal or family history of cancer. She underwent a colonoscopy in November 2019 that showed two lesions. The first measured

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“…В 2023 г. впервые сообщено об успешных родах после транспозиции матки [1]. Это инновационный метод в оперативной гинекологии, который позволяет сохранить репродуктивное здоровье женщин, нуждающихся, например, в лучевой терапии.…”

Section: новости репродуктивной медицины дайджест публикаций за 2023 ...unclassified

Reproductive medicine news. Digest of publications for 2023

Barmina

2023

BRH

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This issue of reproductive medicine news presents the most relevant meta-analysis data, as well as innovative methods in the treatment of diseases of the reproductive system, presented in leading international periodicals in 2023. The present issue includes 5 most actual headings chosen according to editing stuff’s professional opinion. The present digest includes conclusions of the clinical recommendations of the European Society for Human Reproduction (ESHRE) on the management of married couples with recurrent implantation failures, features of SARS-CoV-2 influence on reproductive system and HRT success rate, features of social stress on fetal survival, postnatal outcomes after using of HRT are also briefly formulated.

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First live birth after uterine transposition

Cited by 10 publications

References 22 publications

Utero-ovarian transposition before pelvic radiation in a patient with rectal cancer: a case report and systemic literature review

Utero-ovarian transposition before pelvic radiation in a patient with rectal cancer: a case report and systemic literature review

Uterine transposition and successful pregnancy in a patient with rectal cancer

Reproductive medicine news. Digest of publications for 2023

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