First principle approach towards logic design using hydrogen‐doped single‐strand DNA

Roy, Provas Kumar; Dey, Debarati; De, Debashis

doi:10.1049/iet-nbt.2018.5027

Cited by 6 publications

(2 citation statements)

References 34 publications

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“…It gives the functional value true ( 1 ) if both functional arguments (input signals) have the same logical value ( 0 , 0 or 1 , 1 ), and false ( 0 ) if they are different ( 0 , 1 or 1 , 0 ). This function is highly important in many electronic system, but rarely realized in molecular and biomolecular systems, except a few DNA‐based computing systems, including one designed with pH as an external modulator for DNA intercalation . More sophistical biological systems have been reported for realization of the NXOR gate in cellular neural networks …”

Section: Discussionmentioning

confidence: 99%

Not‐XOR (NXOR) Logic Gate Realized with Enzyme‐Catalyzed Reactions: Optical and Electrochemical Signal Transduction

2019

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The studied enzyme‐based biocatalytic system mimics NXOR Boolean logic gate, which is a logical operator that corresponds to equality in Boolean algebra. It gives the functional value true (1) if both functional arguments (input signals) have the same logical value (0,0 or 1,1), and false (0) if they are different (0,1 or 1,0). The output signal producing reaction is catalyzed by pyrroloquinoline quinone‐dependent glucose dehydrogenase (PQQ‐GDH), which is inhibited at acidic and basic pH values. Two other reactions catalyzed by esterase and urease produce acetic acid and ammonium hydroxide, respectively, shifting solution pH from the optimum pH for PQQ‐GDH to acidic and basic values (1,0 and 0,1 input combinations, respectively), thus switching the enzyme activity off (output 0). When the input signals are not applied (0,0 combination) or both applied compensating each other (1,1 combination) the optimum pH is preserved, thus keeping PQQ‐GDH running at the high rate (output 1). The biocatalytic cascade mimicking the NXOR gate was characterized optically and electrochemically. In the electrochemical experiments the PQQ‐GDH enzyme communicated electronically with a conducting electrode support, thus resulting in the electrocatalytic current when signal combinations 0,0 and 1,1 were applied. The logic gate operation, when it was realized electrochemically, was also extended to the biomolecular release controlled by the gate. The release system included two electrodes, one performing the NXOR gate and another one activated for the release upon electrochemically stimulated alginate hydrogel dissolution. The studied system represents a general approach to the biocatalytic realization of the NXOR logic gate, which can be included in different catalytic cascades mimicking operation of concatenated gates in sophisticated logic circuitries.

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Section: Discussionmentioning

confidence: 99%

Not‐XOR (NXOR) Logic Gate Realized with Enzyme‐Catalyzed Reactions: Optical and Electrochemical Signal Transduction

2019

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“…The electrical doping procedure is the method by which a potential difference has been created between the two ends of the nanodevice. In this theoretical work [47][48][49][50][51][52] we have arranged this by providing different polarity but same-valued voltage at the two ends of the nanodevice via two-probe electrodes. The schematic diagram for this theoretical process is shown in Fig.…”

Section: Mismatching Of Compatibility Between Foreign Atoms and Host Atoms No Probability Of Compatibility Mismatching As It Depends On Bmentioning

confidence: 99%

Electrically Doped Nanoscale Devices Using First-Principle Approach: A Comprehensive Survey

Dey

Ahmadian

et al. 2021

Nanoscale Res Lett

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Doping is the key feature in semiconductor device fabrication. Many strategies have been discovered for controlling doping in the area of semiconductor physics during the past few decades. Electrical doping is a promising strategy that is used for effective tuning of the charge populations, electronic properties, and transmission properties. This doping process reduces the risk of high temperature, contamination of foreign particles. Significant experimental and theoretical efforts are demonstrated to study the characteristics of electrical doping during the past few decades. In this article, we first briefly review the historical roadmap of electrical doping. Secondly, we will discuss electrical doping at the molecular level. Thus, we will review some experimental works at the molecular level along with we review a variety of research works that are performed based on electrical doping. Then we figure out importance of electrical doping and its importance. Furthermore, we describe the methods of electrical doping. Finally, we conclude with a brief comparative study between electrical and conventional doping methods.

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Implementation of biomolecular logic gate using DNA and electrically doped GaAs nano-pore: a first principle paradigm

Dey

Roy

2021

J Mol Model

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First principle approach towards logic design using hydrogen‐doped single‐strand DNA

Cited by 6 publications

References 34 publications

Not‐XOR (NXOR) Logic Gate Realized with Enzyme‐Catalyzed Reactions: Optical and Electrochemical Signal Transduction

Not‐XOR (NXOR) Logic Gate Realized with Enzyme‐Catalyzed Reactions: Optical and Electrochemical Signal Transduction

Electrically Doped Nanoscale Devices Using First-Principle Approach: A Comprehensive Survey

Implementation of biomolecular logic gate using DNA and electrically doped GaAs nano-pore: a first principle paradigm

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